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Identification of novel cis-regulatory elements of eya1 in xenopus laevis using bac recombineering
(Springer Nature, 2017-11-03)
The multifunctional Eya1 protein plays important roles during the development of cranial sensory organs and ganglia, kidneys, hypaxial muscles and several other organs in vertebrates. Eya1 is encoded by a complex locus ...
<i>phip</i> - a novel candidate breast cancer susceptibility locus on 6q14.1
(Impact Journals, LLC, 2017-11-28)
Most non-BRCA1/2 breast cancer families have no identified genetic cause. We used linkage and haplotype analyses in familial and sporadic breast cancer cases to identify a susceptibility locus on chromosome 6q. Two independent ...
Towards precision medicine: discovering novel gynecological cancer biomarkers and pathways using linked data
(Springer Nature, 2017-09-19)
Background: Next Generation Sequencing (NGS) is playing a key role in therapeutic decision making for the cancer prognosis and treatment. The NGS technologies are producing a massive amount of sequencing datasets. Often, ...