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Inhibition of nedd8-activating enzyme: a novel approach for the treatment of acute myeloid leukemia
(American Society of Hematology, 2010-03-04)
NEDD8 activating enzyme (NAE) has been identified as an essential regulator of the NEDD8 conjugation pathway, which controls the degradation of many proteins with important roles in cell-cycle progression, DNA damage, and ...