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Chondrogenic differentiation increases antidonor immune response to allogeneic mesenchymal stem cell transplantation
(Elsevier BV, 2014-03-01)
Allogeneic mesenchymal stem cells (allo-MSCs) have potent regenerative and immunosuppressive potential and are being investigated as a therapy for osteoarthritis; however, little is known about the immunological changes ...
Changes in immunological profile of allogeneic mesenchymal stem cells after differentiation: should we be concerned?
(Springer Nature, 2014-01-01)
Mesenchymal stem cells (MSCs) are an adult stromal cell population possessing potent differentiation capacity and a potential for use across major histocompatibility complex barriers. Although allogeneic MSCs have potent ...
Donor bone marrow–derived dendritic cells prolong corneal allograft survival and promote an intragraft immunoregulatory milieu
(Elsevier BV, 2013-11-01)
Investigations into cell therapies for application in organ transplantation have grown. Here, we describe the ex vivo generation of donor bone marrow-derived dendritic cells (BMDCs) and glucocorticoid-treated BMDCs with ...