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A randomised controlled trial of an exercise plus behaviour change intervention in people with multiple sclerosis: the step it up study protocol
(Springer Nature, 2014-12-01)
Background: Exercise has consistently yielded short-term, positive effects on health outcomes in people with multiple sclerosis (MS). However, these effects have not been maintained in the long-term. Behaviour change ...
Assessing methods to specify the target difference for a randomised controlled trial: delta (difference elicitation in trials) review
(National Institute for Health Research, 2014-01-01)
Background: The randomised controlled trial (RCT) is widely considered to be the gold standard study for comparing the effectiveness of health interventions. Central to the design and validity of a RCT is a calculation of ...
Exploring the feasibility and acceptability of couple-based psychosexual support following prostate cancer surgery: study protocol for a pilot randomised controlled trial
(Springer Nature, 2014-01-01)
Background: Men who undergo surgery for prostate cancer frequently experience significant side-effects including urinary and sexual dysfunction. These difficulties can lead to anxiety, depression and reduced quality of ...
Does lowering blood pressure with antihypertensive therapy preserve independence in activities of daily living? a systematic review
(Oxford University Press (OUP), 2014-08-25)
BACKGROUND
Hypertension is a major risk factor for functional impairment. Dependence is an important related outcome for older adults, but outcomes in hypertension trials appear to focus primarily on major vascular events. ...
The magnitude and characteristics of the population of cancer survivors: using population-based estimates of cancer prevalence to inform service planning for survivorship care
(Springer Nature, 2014-10-15)
Background: Rising cancer incidence and survival mean that the number of cancer survivors is growing. Accumulating evidence suggests many survivors have long-term medical and supportive care needs, and that these needs ...
Body mass index and health service utilisation in the older population: results from the irish longitudinal study on ageing
(Oxford University Press (OUP), 2014-11-06)
Background: obesity is associated with higher healthcare costs in older people; however, estimates are predominantly based on the use of primary and secondary services. Our objective was to estimate the effect of overweight ...
Stress and self-efficacy predict psychological adjustment at diagnosis of prostate cancer
(Springer Nature, 2014-07-04)
Prostate cancer is the most frequently non-skin cancer diagnosed among men. Diagnosis, a significant burden, generates many challenges which impact on emotional adjustment and so warrants further investigation. Most studies ...