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Don't lose heart - therapeutic value of apoptosis prevention in the treatment of cardiovascular disease
(Wiley-Blackwell, 2005-07-01)
Cardiovascular disease is a leading cause of death worldwide. Loss of function or death of cardiomyocytes is a major contributing factor to these diseases. Cell death in conditions such as heart failure and myocardial ...
The mitochondrial death pathway: a promising therapeutic target in diseases
(Wiley-Blackwell, 2009-07-01)
The mitochondrial pathway to apoptosis is a major pathway of physiological cell death in vertebrates. The mitochondrial cell death pathway commences when apoptogenic molecules present between the outer and inner mitochondrial ...