dc.contributor.author | O'Keeffe, S. T. | |
dc.date.accessioned | 2018-08-24T08:25:56Z | |
dc.date.available | 2018-08-24T08:25:56Z | |
dc.date.issued | 2005-07-01 | |
dc.identifier.citation | O'Keeffe, S. T. (2005). Secondary causes of restless legs syndrome in older people. Age and Ageing 34 (4), 349-352 | |
dc.identifier.issn | 0002-0729,1468-2834 | |
dc.identifier.uri | http://hdl.handle.net/10379/9654 | |
dc.description.abstract | Background: secondary causes of restless legs syndrome (RLS) have been reported to be more common in those with late-onset RLS. However, 'late-onset' in previous studies was defined as onset after 45 years.
Objective: to determine the prevalence of secondary causes of RLS and the relationship between aetiological factors and age of symptom onset in an older population.
Design: prospective study conducted over a 5-year period.
Participants: 80 consecutive non-related patients diagnosed with RLS.
Measurements: patients were assessed according to a standard protocol. Age at symptom onset, severity of symptoms, neurological findings and laboratory tests were examined.
Results: iron deficiency (serum ferritin <50 ng/ml) was present in 22% of patients with onset before 50 years, 39% of those with onset at 50 to 64 years and 58% in those with onset after 64 years (P=0.009). Clinical neuropathy was also more common in older-onset patients (P= 0.08). Family history was positive in 39%, 23% and 8% of these groups, respectively (P= 0.008).
Conclusion: secondary causes of RLS become more common and a positive family history less common with increased age, of symptom onset. | |
dc.publisher | Oxford University Press (OUP) | |
dc.relation.ispartof | Age and Ageing | |
dc.rights | Attribution-NonCommercial-NoDerivs 3.0 Ireland | |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/3.0/ie/ | |
dc.subject | restless legs syndrome | |
dc.subject | elderly | |
dc.subject | iron | |
dc.subject | ferritin | |
dc.subject | iron | |
dc.subject | population | |
dc.subject | symptoms | |
dc.subject | memo | |
dc.subject | risk | |
dc.title | Secondary causes of restless legs syndrome in older people | |
dc.type | Article | |
dc.identifier.doi | 10.1093/ageing/afi066 | |
dc.local.publishedsource | https://academic.oup.com/ageing/article-pdf/34/4/349/29065/afi066.pdf | |
nui.item.downloads | 0 | |