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Now showing items 1-6 of 6
In memory of Tom Isaacs: The epitomical mover and shaker
(Wiley, 2018-10-16)
[No abstract available]
A role for viral infections in Parkinson's etiology?
(Portland Press, 2018-04-16)
Despite over 200 years since its first description by James Parkinson, the cause(s) of most cases of Parkinson’s disease (PD) are yet to be elucidated. The disparity between the current understanding of PD symptomology and ...
Brain repair for Parkinson's disease: is the answer in the matrix?
(Medknow Publications, 2018-07-13)
Two hundred years after James Parkinson first described the cardinal
motor symptoms of the disorder that would later bear his name, there
is still an irrefutable need for a therapy that targets the underlying
pathophysiology ...
The prefrontal cortical endocannabinoid system modulates fear–pain interactions in a subregion‐specific manner
(Wiley, 2018-05-30)
Background and Purpose
The emotional processing and coordination of top‐down responses to noxious and conditioned aversive stimuli involves the medial prefrontal cortex (mPFC). Evidence suggests that subregions of the ...
Locomotor and anti-immobility effects of buprenorphine in combination with the opioid receptor modulator samidorphan in rats
(Elsevier, 2018-12-13)
Modulation of the opioid system has re-emerged as a potential therapeutic avenue for treating depression, with efficacy of a fixed-dose combination of buprenorphine (BUP), a partial mu-opioid receptor (MOR) agonist and ...
PPARs and pain
(Wiley, 2018-04-21)
Chronic pain is a common cause of disability worldwide and remains a global health and socio-economic challenge. Current analgesics are either ineffective in a significant proportion of patients with chronic pain or ...