Browsing Pharmacology & Therapeutics (Scholarly Articles) by Subject "Periaqueductal grey"
Now showing items 1-3 of 3
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Effects of direct periaqueductal grey administration of a cannabinoid receptor agonist on nociceptive and aversive responses in rats
(Elsevier, 2003-07-31)The analgesic potential of cannabinoids may be hampered by their ability to produce aversive emotion when administered systemically. We investigated the hypothesis that the midbrain periaqueductal grey (PAG) is a common ... -
The endocannabinoid system in the rat dorsolateral periaqueductal grey mediates fear-conditioned analgesia and controls fear expression in the presence of nocicpetive tone
(Wiley, 2011)Background and purpose: Endocannabinoids in the midbrain periaqueductal grey (PAG) are involved in modulating nociception and unconditioned stress-induced analgesia, however, their role in fear-conditioned analgesia (FCA) ... -
Genotype-dependent responsivity to inflammatory pain: A role for TRPV1 in the periaqueductal grey
(Elsevier, 2016-08-09)Negative affective state has a significant impact on pain, and genetic background is an important moderating influence on this interaction. The Wistar-Kyoto (WKY) inbred rat strain exhibits a stress-hyperresponsive, ...