Browsing Pharmacology & Therapeutics by Author "Corcoran, Louise"
Now showing items 1-3 of 3
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Attenuation of fear‐conditioned analgesia in rats by monoacylglycerol lipase inhibition in the anterior cingulate cortex: Potential role for CB2 receptors
Corcoran, Louise; Mattimoe, Darragh; Roche, Michelle; Finn, David P. (The British Pharmacological Society, 2020-01-22)Improved understanding of brain mechanisms regulating endogenous analgesia is important from a fundamental physiological perspective and for identification of novel therapeutic strategies for pain. The endocannabinoid ... -
The prefrontal cortical endocannabinoid system modulates fear–pain interactions in a subregion‐specific manner
Rea, Kieran; McGowan, Fiona; Corcoran, Louise; Roche, Michelle; Finn, David P. (Wiley, 2018-05-30)Background and Purpose The emotional processing and coordination of top‐down responses to noxious and conditioned aversive stimuli involves the medial prefrontal cortex (mPFC). Evidence suggests that subregions of the ... -
The role of the brain's endocannabinoid system in pain and its modulation by stress
Corcoran, Louise; Roche, Michelle; Finn, David P. (Elsevier, 2015-11-06)Stress has a complex, bidirectional modulatory influence on pain. Stress may either reduce (stress-induced analgesia) or exacerbate (stress-induced hyperalgesia) pain depending on the nature, duration, and intensity of the ...