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Minocycline modulates neuropathic pain behaviour and cortical M1-M2 microglial gene expression in a rat model of depression
(Elsevier, 2014-11)
There is a paucity of data on the role of microglia and neuroinflammatory processes in the association between chronic pain and depression. The current study examined the effect of the microglial inhibitor minocycline on ...
The very first requirement of treatment is that it should do no harm†, so why are antibiotics still overprescribed?
(Wiley, 2014-01-26)
[No abstract available]
Distribution of tract deficits in schizophrenia
(BioMed Central, 2014-04-02)
Background: Gray and white matter brain changes have been found in schizophrenia but the anatomical organizing process underlying these changes remains unknown. We aimed to identify gray and white matter volumetric changes ...
Reasons for participation and non-participation in a diabetes prevention trial among women with prior gestational diabetes mellitus (GDM)
(Springer, 2014-01)
Background: Gestational diabetes mellitus (GDM) is a risk factor for the development of type 2 diabetes. Lifestyle intervention can prevent progression to type 2 diabetes in high risk populations. We designed a randomised ...
Screening uptake rates and the clinical and cost effectiveness of screening for gestational diabetes mellitus in primary versus secondary care: study protocol for a randomised controlled trial
(BioMed Central, 2014-01-17)
Background: The risks associated with gestational diabetes mellitus (GDM) are well recognized, and there is increasing evidence to support treatment of the condition. However, clear guidance on the ideal approach to screening ...
ATLANTIC-DIP- Prevalence of metabolic syndrome and insulin resistance in women with previous gestational diabetes mellitus by International Association of Diabetes in Pregnancy Study Groups criteria
(Springer, 2014-07-08)
Women with previous gestational diabetes (GDM) are a high-risk group for future development of diabetes, metabolic syndrome, and cardiovascular disease. The new International Association of Diabetes in Pregnancy Study ...
Short and long-term effects of gestational diabetes mellitus on the health care cost: cross-sectional comparative study in the ATLANTIC DIP Cohort
(2014-10-21)
Previous gestational diabetes (GDM) is associated with a significant lifetime risk of type 2
diabetes. We assessed the performance of HbA1c and fasting plasma glucose (FPG) against 75g oral glucose tolerance testing (OGTT) ...
Screening uptake rates and the clinical and cost effectiveness of screening for gestational diabetes mellitus in primary versus secondary care: study protocol for a randomised controlled trial
(BioMed Central, 2014-01-17)
The risks associated with gestational diabetes mellitus (GDM) are well recognized, and there is increasing evidence to support treatment of the condition. However, clear guidance on the ideal approach to screening for GDM ...
Interns and their smartphones: use for clinical practice
(Medscape, 2014)
Purpose of the study Smartphone use among healthcare professionals has become widespread and will continue to grow in the coming years.Study design In October 2012, a survey was distributed to 230 interns at two of the ...
Recent Rape/Sexual Assault: National Guidelines on Referral and Forensic Clinical Examination
(Health Service Executive and Department of Justice and Law Reform, 2014)