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Analysis of thermal effects from pulsed field ablation
(Oxford University Press, 2023-11-09)
Background
Pulsed field ablation (PFA) has been described as non-thermal, but abundant data exist in oncology applications [1-3], and growing data are emerging in cardiology [4], highlighting that thermal effects are in ...
Cardioneuroablation using epicardial pulsed field ablation for the treatment of atrial fibrillation
(MDPI, 2023-05-29)
Atrial fibrillation (AF) is the most common cardiac arrhythmia affecting millions of people worldwide. The cardiac autonomic nervous system (ANS) is widely recognized as playing a key role in both the initiation and ...
How intramyocardial fat can alter the electric field distribution during Pulsed Field Ablation (PFA): Qualitative findings from computer modeling
(Public Library of Science, 2023-11-02)
Even though the preliminary experimental data suggests that cardiac Pulsed Field Ablation (PFA) could be superior to radiofrequency ablation (RFA) in terms of being able to ablate the viable myocardium separated from the ...
Low-frequency electrical conductivity of trabecular bone: Insights from in silico modeling
(MDPI, 2023-09-23)
Background: The electrical conductivity of trabecular bone at 100 kHz has recently been reported as a good predictor of bone volume fraction. However, quantifying its relationship with free water (or physiological solution) ...
Difference between endocardial and epicardial application of pulsed fields for targeting Epicardial Ganglia: An in-silico modelling study
(Elsevier, 2024-04-20)
Background
Pulsed Field Ablation (PFA) has recently been proposed as a non-thermal energy to treat atrial fibrillation by selective ablation of ganglionated plexi (GP) embedded in epicardial fat. While some of PFA-technologies ...
Disturbing effect of intra-tissue temperature sensors in pre-clinical experimental studies of radiofrequency cardiac ablation: A computer-based modeling study
(MDPI, 2023-04-11)
Background: Preclinical studies on radiofrequency (RF) cardiac ablation (RFCA) use very small temperature sensors in specific positions in the tissue subjected to RF heating. Despite the sensors¿ small size, the proximity ...