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Chronic administration of amitriptyline differentially alters neuropathic pain-related behaviour in the presence and absence of a depressive-like phenotype
(Elsevier, 2015-02)
Chronic pain and depression share a complex, reciprocal relationship. Furthermore, in addition to treating depression, antidepressants such as amitriptyline are a first-line treatment for chronic pain conditions, indicating ...
Intervention to improve the quality of antimicrobial prescribing for urinary tract infection: a cluster randomized trial
(Canadian Medical Association, 2015-11-16)
Background: Overuse of antimicrobial therapy in the community adds to the global spread of antimicrobial resistance, which is jeopardizing the treatment of common infections.Methods: We designed a cluster randomized complex ...
Cognitive course in first-episode psychosis and clinical correlates: A 4year longitudinal study using the MATRICS Consensus Cognitive Battery.
(2015-09-26)
While cognitive impairments are prevalent in first-episode psychosis, the course of these deficits is not fully understood. Most deficits appear to remain stable, however there is uncertainty regarding the trajectory of ...
Application of video-based methods for competitive swimming analysis: a systematic review
(2015)
This paper explores the application of video-based methods for the analysis of com- petitive swimming performance. A systematic search of the existing literature was conducted using the following keywords: swim*, performance, ...
Neuroinflammatory mechanisms linking pain and depression
(Karger, 2015)
Depression and chronic pain have been estimated to co-occur in up to 80% of patients suffering from these disorders, with this co-morbidity being more disabling and more expensive to both patients and society than either ...
Impact of working 48 hours per week on opportunities for training and patient contact: the experience of Irish interns
(Oxford University Press, 2015-09-29)
Objective. The European Working Time Regulations (EWTR) have been criticised for its
purported negative impact on the training of junior doctors. The aim of this study was to examine
the amount of time interns spent ...
The efficacy of mindfulness-based interventions in primary care: a meta-analytic review
(Annals of Family Medicine, 2015-07-16)
PURPOSE Positive effects have been reported after mindfulness-based interventions (MBIs) in diverse clinical and nonclinical populations. Primary care is a key health care setting for addressing common chronic conditions, ...
Do general practitioners prescribe more antimicrobials when the weekend comes?
(SpringerOpen, 2015-11-24)
Inappropriate antimicrobial prescribing contributes to the global spread of antimicrobial resistance. The pending weekend with changed availability of general practitioners (GP) and increased patient concern may increase ...
Inertial sensor technology for elite swimming performance analysis: a systematic review
(MDPI, 2015-12-25)
Technical evaluation of swimming performance is an essential factor of elite athletic preparation. Novel methods of analysis, incorporating body worn inertial sensors (i.e., Microelectromechanical systems, or MEMS, ...
Medical speciality choices: Does personality matter?
(Irish Medical Journal, 2015-08-07)
There has been
increasing interest in the personalities of doctors. This study examined
whether personality differed based upon gender, level of training or medical
speciality among 200 physicians and 134 medical students. ...