Browsing School of Medicine by Author "Killilea, Marykate"
Now showing items 1-2 of 2
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Exacerbated LPS/GalN-induced liver injury in the stress-sensitive Wistar Kyoto rat is associated with changes in the endocannabinoid system
Killilea, Marykate; Kerr, Daniel M.; Mallard, Beth M.; Roche, Michelle; Wheatley, Antony M. (MDPI, 2020-08-23)Acute liver injury (ALI) is a highly destructive and potentially life-threatening condition, exacerbated by physical and psychological stress. The endocannabinoid system plays a key role in modulating stress and hepatic ... -
Pharmacological inhibition of FAAH modulates TLR-induced neuroinflammation, but not sickness behaviour: An effect partially mediated by central TRPV1
Henry, Rebecca J.; Kerr, Daniel M.; Flannery, Lisa E.; Killilea, Marykate; Hughes, Edel M.; Corcoran, Louise; Finn, David P.; Roche, Michelle (Elsevier, 2017-02-22)Aberrant activation of toll-like receptors (TLRs), key components of the innate immune system, has been proposed to underlie and exacerbate a range of central nervous system disorders. Increasing evidence supports a role ...