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Chronic administration of amitriptyline differentially alters neuropathic pain-related behaviour in the presence and absence of a depressive-like phenotype
(Elsevier, 2015-02)
Chronic pain and depression share a complex, reciprocal relationship. Furthermore, in addition to treating depression, antidepressants such as amitriptyline are a first-line treatment for chronic pain conditions, indicating ...
The cost effectiveness of the SIMPle intervention to improve antimicrobial prescribing for urinary tract infection in primary care
(Oxford University Press, 2016-09-27)
Abstract
Background
Antimicrobial resistance is a major public health issue. This study examines the cost effectiveness of the SIMPle (Supporting the Improvement and Management of Prescribing for Urinary Tract Infections ...
Using mobile phones to collect patient data: lessons learned from the SIMPle study
(JMIR Publications, 2017-04-25)
Background: Mobile phones offer new opportunities to efficiently and interactively collect real-time data from patients with acute illnesses, such as urinary tract infections (UTIs). One of the main benefits of using mobile ...
Adverse events of fluoroquinolones vs. other antimicrobials prescribed in primary care: A systematic review and meta-analysis of randomized controlled trials
(Elsevier, 2018-04-25)
Background
Fluoroquinolones (FQs) are second line antimicrobial agents. Once the decision to prescribe
an antimicrobial is made, its choice should be based on both the benefits and harms. This
systematic review quantifies ...
The efficacy of mindfulness-based interventions in primary care: a meta-analytic review
(Annals of Family Medicine, 2015-07-16)
PURPOSE Positive effects have been reported after mindfulness-based interventions (MBIs) in diverse clinical and nonclinical populations. Primary care is a key health care setting for addressing common chronic conditions, ...
Do general practitioners prescribe more antimicrobials when the weekend comes?
(SpringerOpen, 2015-11-24)
Inappropriate antimicrobial prescribing contributes to the global spread of antimicrobial resistance. The pending weekend with changed availability of general practitioners (GP) and increased patient concern may increase ...
Adverse effects of amoxicillin for acute lower respiratory tract infection in primary care: Secondary and subgroup analysis of a randomised clinical trial
(MDPI, 2017-12-13)
A European placebo-controlled trial of antibiotic treatment for lower respiratory tract infection (LRTI) conducted in 16 primary care practices networks recruited participants between November 2007 and April 2010, and found ...
Lived experiences of fibromyalgia
(RCN Publishing, 2015-02-10)
Martina Diviney and Maura Dowling explain why this chronic illness can take a long time to diagnose and how assessment tools can be used to speed up the process
This phenomenological study explored the lived experience ...
Public health nurses' (PHNs) experiences of their role as part of a primary care team (PCT) in Ireland
(Australian Nursing and Midwifery Federation, 2015-03)
ObjectiveThis study aimed to understand public health nurses' (PHNs) views and experiences of their role as part of a primary care team (PCT) and developments within primary care.DesignThe study adopted a qualitative design ...
Screening uptake rates and the clinical and cost effectiveness of screening for gestational diabetes mellitus in primary versus secondary care: study protocol for a randomised controlled trial
(BioMed Central, 2014-01-17)
Background: The risks associated with gestational diabetes mellitus (GDM) are well recognized, and there is increasing evidence to support treatment of the condition. However, clear guidance on the ideal approach to screening ...