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Supporting systems innovation
(World Scientific Publishing, 2000)
Many researchers and practitioners contend that organisations should respond to changing market need and create competitive advantage through innovation and creativity. Each year, organisations expend significant resources ...
Overview of the regulation of medical devices and drugs in the European Union and the United States
(SAGE Publications, 2013-08-06)
This article provides an overview of the regulation of medical devices and drugs in the European Union and the US. It is important for all stakeholders involved in bringing a medical device or drugs to market to have an ...
The Internet of Things: why now, and what's next?
(IEEE, 2016-01)
The technology to connect "things" to the Internet has existed for more than 20 years, so if we take a look back at recent history, we might well be tempted to ask the question "Why now" In this article, I address that ...
Development of a Global Energy Management System for non-energy intensive multi-site industrial organisations: A methodology
(Elsevier, 2017-01-25)
For multi-site organisations, informed decision making on capital investment aimed at improving energy performance and cutting carbon emissions, across a global site base, is a complex problem. This work presents the ...
Investigation of the optimal timing for chondrogenic priming of MSCs to enhance osteogenic differentiation in vitro as a bone tissue engineering strategy
(Wiley, 2013-08-07)
Recent in vitro tissue engineering approaches have shown that
chondrogenic priming of human bone marrow mesenchymal stem cells (MSCs)
can have a positive effect on osteogenesis in vivo. However, whether
chondrogenic ...
Iris authentication in handheld devices - considerations for constraint-free acquisition
(IEEE, 2015-05)
As a near ideal biometric, iris authentication is widely used and mobile acquisition techniques are known. But iris acquisition on handheld imaging devices, such as smartphones, poses multiple, unique challenges. In this ...
Influence of seasonal circulation on flushing of the Irish Sea
(Elsevier ScienceDirect, 2009-12-16)
We applied a three-dimensional general ocean and coastal circulation model to the Irish Sea in order to determine water renewal time scales in the region. The model was forced with meteorological data for 1995, a year with ...
System dynamics modelling to support policy analysis for sustainable health care
(2014)
System dynamics (SD) is an established simulation methodology used to explore the behaviour of social systems over time. The field has addressed challenging sustainability problems in fisheries, urban planning and environmental ...
Cooperative contractility: the role of stress fibres in the regulation of cell-cell junctions
(Elsevier, 2014-11-27)
We present simulations of cell-cell adhesion as reported in a recent study [Liu et al., 2010, PNAS, 107(22), 9944-9] for two cells seeded on an array of micro-posts. The micro-post array allows for the measurement of forces ...
Altered mechanical environment of bone cells in an animal model of short- and long-term osteoporosis
(Biophysical Society, 2015-04-07)
Alterations in bone tissue composition during osteoporosis likely disrupt the mechanical environment of bone cells and may thereby initiate a mechanobiological response. It has proved challenging to characterize the ...