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    AuthorMcNamara, Laoise M. (4)Vaughan, Ted J. (2)Verbruggen, Stefaan W. (2)Barry, F.P. (1)Birmingham, Evelyn (1)... View MoreSubject
    Biomedical engineering (4)
    Bone (4)
    Osteocyte (4)
    In vitro (2)Lacuna (2)... View MoreDate Issued2015 (1)2013 (1)2012 (2)TypeArticle (4)

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    Fluid flow in the osteocyte mechanical environment: a fluid-structure interaction approach 

    Verbruggen, Stefaan W.; Vaughan, Ted J.; McNamara, Laoise M. (Springer Verlag, 2013-04-09)
    Osteocytes are believed to be the primary sensor of mechanical stimuli in bone, which orchestrate osteoblasts and osteoclasts to adapt bone structure and composition to meet physiological loading demands. Experimental ...
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    Strain amplification in bone mechanobiology: a computational investigation of the in vivo mechanics of osteocytes 

    Verbruggen, Stefaan W.; Vaughan, Ted J.; McNamara, Laoise M. (The Royal Society Publishing, 2012-06-06)
    The osteocyte is believed to act as the main sensor of mechanical stimulus in bone, controlling signalling for bone growth and resorption in response to changes in the mechanical demands placed on our bones throughout life. ...
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    Osteogenic differentiation of mesenchymal stem cells is regulated by osteocyte and osteoblast cells in a simplified bone niche 

    Birmingham, Evelyn; Niebur, G.L.; McHugh, Peter E.; Shaw, G.; Barry, F.P.; McNamara, Laoise M. (AO Research Institute Davos, 2012)
    Mesenchymal stem cells (MSCs) within their native environment of the stem cell niche in bone receive biochemical stimuli from surrounding cells. These stimuli likely influence how MSCs differentiate to become bone precursors. ...
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    Differential β3 and β1 integrin expression in bone marrow and cortical bone of estrogen deficient rats 

    Voisin, Muriel C.; McNamara, Laoise M. (Wiley, 2015-08-12)
    Integrin-based (beta(3)) attachments to the extracellular matrix (ECM) on osteocyte cell processes have recently been proposed to play an important role in facilitating osteocyte mechanosensation. However, it is not yet ...
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