Now showing items 1-4 of 4
miR-379 Regulates Cyclin B1 Expression and Is Decreased in Breast Cancer
MicroRNAs are small non-coding RNA molecules that control gene expression post-transcriptionally, and are known to be altered in many diseases including breast cancer. The aim of this study was to determine the relevance ...
Influence of stromal–epithelial interactions on breast cancer in vitro and in vivo
Stromal cell-secreted chemokines including CCL2 have been implicated in the primary tumor microenvironment, as mediators of tumor cell migration, proliferation, and angiogenesis. Expression of CCL2 and its principal receptor ...
Screening of exosomal microRNAs from colorectal cancer cells
(IOS Press, 2017-01-03)
BACKGROUND: Cells release extracellular membrane vesicles including microvesicles known as exosomes. Exosomes contain microRNAs (miRNAs) however the full range within colorectal cancer cell secreted exosomes is unknown.OBJECTIVE: ...
Isolation of secreted microRNAs (miRNAs) from cell-conditioned media
MicroRNAs (miRNAs) have been found to be stable in the circulation of cancer patients raising their potential as circulating biomarkers of disease. The specific source and role, however, of miRNAs in the circulation is ...