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Identification and validation of mirnas as endogenous controls for rq-pcr in blood specimens for breast cancer studies
(Public Library of Science (PLoS), 2013-12-31)
Introduction: A prerequisite to accurate interpretation of RQ-PCR data is robust data normalization. A commonly used method is to compare the cycle threshold (C-T) of target miRNAs with those of a stably expressed endogenous ...
Gene therapy: pursuing restoration of dermal adhesion in recessive dystrophic epidermolysis bullosa
(Wiley-Blackwell, 2013-12-30)
The replacement of a defective gene with a fully functional copy is the goal of the most basic gene therapy. Recessive dystrophic epidermolysis bullosa (RDEB) is characterised by a lack of adhesion of the epidermis to the ...
Autologous circulating angiogenic cells treated with osteopontin and delivered via a collagen scaffold enhance wound healing in the alloxan-induced diabetic rabbit ear ulcer model
(Springer Nature, 2013-01-01)
Introduction: Diabetic foot ulceration is the leading cause of amputation in people with diabetes mellitus. Peripheral vascular disease is present in the majority of patients with diabetic foot ulcers. Despite standard ...