Browsing Externally hosted open access publications with University of Galway authors (2) by Subject "unfolded-protein-response"
Now showing items 1-2 of 2
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Endoplasmic reticulum stress induces ligand-independent tnfr1-mediated necroptosis in l929 cells
(Springer Nature, 2015-01-08)Endoplasmic reticulum (ER) stress-induced cellular dysfunction and death is associated with several human diseases. It has been widely reported that ER stress kills through activation of the intrinsic mitochondrial apoptotic ... -
Ripk1 promotes death receptor-independent caspase-8-mediated apoptosis under unresolved er stress conditions
(Springer Nature, 2014-12-04)Accumulation of unfolded proteins in the endoplasmic reticulum (ER) causes ER stress and results in the activation of the unfolded protein response (UPR), which aims at restoring ER homeostasis. However, when the stress ...