Browsing Externally hosted open access publications with University of Galway authors (2) by Subject "immune-response"

Now showing items 1-9 of 9

    • A differential interplay between the expression of th1/th2/treg related cytokine genes in teladorsagia circumcincta infected drb1*1101 carrier lambs 

      Hassan, Musa; Hanrahan, James P; Good, Barbara; Mulcahy, Grace; Sweeney, Torres (Springer Nature, 2011-01-01)
      Substantial debate exists on whether the immune response between sheep resistant and susceptible to gastrointestinal nematodes can be differentiated into a Th1 and Th2 phenotype. The present study addresses the hypothesis ...

    • Assessment of the duration of protection in campylobacter jejuni experimental infection in humans 

      Tribble, D. R.; Baqar, S.; Scott, D. A.; Oplinger, M. L.; Trespalacios, F.; Rollins, D.; Walker, R. I.; Clements, J. D.; Walz, S.; Gibbs, P.; Burg, E. F.; Moran, A. P.; Applebee, L.; Bourgeois, A. L. (American Society for Microbiology, 2010-01-19)
      A human Campylobacter jejuni infection model provided controlled exposure to assess vaccine efficacy and investigate protective immunity for this important diarrheal pathogen. A well-characterized outbreak strain, C. jejuni ...

    • Elevated herv-k mrna expression in pbmc is associated with a prostate cancer diagnosis particularly in older men and smokers 

      Wallace, Tiffany A.; Downey, Ronan F.; Seufert, Caleb J.; Schetter, Aaron; Dorsey, Tiffany H.; Johnson, Carol A.; Goldman, Radoslav; Loffredo, Christopher A.; Yan, Peisha; Sullivan, Francis J.; Giles, Francis J.; Wang-Johanning, Feng; Ambs, Stefan; Glynn, Sharon A. (Oxford University Press (OUP), 2014-05-23)
      Aberrant expression of subgroup k human endogenous retroviruses (HERV-K) has been observed in prostate cancer. This subgroup is unique because it encodes sequences in the human genome containing open reading frames for ...

    • Immunogenicity of allogeneic mesenchymal stem cells 

      Schu, Sabine; Nosov, Mikhail; O'Flynn, Lisa; Shaw, Georgina; Treacy, Oliver; Barry, Frank; Murphy, Mary; O'Brien, Timothy; Ritter, Thomas (Wiley-Blackwell, 2012-08-23)
      Mesenchymal stem cells (MSCs) inhibit proliferation of allogeneic T cells and express low levels of major histocompatibility complex class I (MHCI), MHCII and vascular adhesion molecule-1 (VCAM-1). We investigated whether ...

    • Impact ofhelicobacter pylorion the healing process of the gastric barrier 

      Mnich, Eliza; Kowalewicz-Kulbat, Magdalena; Sicińska, Paulina; Hinc, Krzysztof; Obuchowski, Michał; Gajewski, Adrian; Moran, Anthony P; Chmiela, Magdalena (Baishideng Publishing Group Inc., 2016-01-01)
      AIM To determine the impact of selected well defined Helicobacter pylori (H. pylori) antigens on gastric barrier cell turnover. METHODS In this study, using two cellular models of gastric epithelial cells and fibroblasts, ...

    • Interaction ofhelicobacter pyloriwith c-type lectin dendritic cell-specific icam grabbing nonintegrin 

      Miszczyk, Eliza; Rudnicka, Karolina; Moran, Anthony P.; Fol, Marek; Kowalewicz-Kulbat, Magdalena; Druszczyńska, Magdalena; Matusiak, Agnieszka; Walencka, Maria; Rudnicka, Wiesława; Chmiela, Magdalena (Hindawi Limited, 2012-01-01)
      In this study we asked whether Helicobacter pylori whole cells and lipopolysaccharide (LPS) utilize sugar moieties of Lewis (Le) antigenic determinants to interact with DC-SIGN (dendritic cell specific ICAM grabbing ...

    • Mesenchymal stem cell effects on t-cell effector pathways 

      Duffy, Michelle M; Ritter, Thomas; Ceredig, Rhodri; Griffin, Matthew D (Springer Nature, 2011-01-01)
      Mesenchymal stem (stromal) cells (MSCs) are rare, multipotent progenitor cells that can be isolated and expanded from bone marrow and other tissues. Strikingly, MSCs modulate the functions of immune cells, including T ...

    • The vibrio parahaemolyticus type iii secretion systems manipulate host cell mapk for critical steps in pathogenesis 

      Matlawska-Wasowska, Ksenia; Finn, Rebecca; Mustel, Ana; O'Byrne, Conor P; Baird, Alan W; Coffey, Eleanor T; Boyd, Aoife (Springer Nature, 2010-01-01)
      Background: Vibrio parahaemolyticus is a food-borne pathogen causing inflammation of the gastrointestinal epithelium. Pathogenic strains of this bacterium possess two Type III Secretion Systems (TTSS) that deliver effector ...

    • Vil-10-overexpressing human mscs modulate naïve and activated t lymphocytes following induction of collagenase-induced osteoarthritis 

      Farrell, Eric; Fahy, Niamh; Ryan, Aideen E; Flatharta, Cathal O; O’Flynn, Lisa; Ritter, Thomas; Murphy, J Mary (Springer Nature, 2016-05-18)
      Background: Recent efforts in osteoarthritis (OA) research have highlighted synovial inflammation and involvement of immune cells in disease onset and progression. We sought to establish the in-vivo immune response in ...