Browsing by Author "Ma, Jun"
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Amyotrophic lateral sclerosis patient ipsc-derived astrocytes impair autophagy via non-cell autonomous mechanisms
Madill, Martin; McDonagh, Katya; Ma, Jun; Vajda, Alice; McLoughlin, Paul; O’Brien, Timothy; Hardiman, Orla; Shen, Sanbing (Springer Nature, 2017-06-13)Amyotrophic lateral sclerosis, a devastating neurodegenerative disease, is characterized by the progressive loss of motor neurons and the accumulation of misfolded protein aggregates. The latter suggests impaired proteostasis ...