Browsing by Author "Cunnea, Paula"
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Increased expression of endoplasmic reticulum stress-related signaling pathway molecules in multiple sclerosis lesions
Mháille, Aoife Ní; McQuaid, Stephen; Windebank, Anthony; Cunnea, Paula; McMahon, Jill; Samali, Afshin; FitzGerald, Una (Oxford University Press (OUP), 2008-03-01)Activation of endoplasmic reticulum (ER) stress-related cell signals has been reported in several neurologic disorders and may contribute to neurodegeneration. Endoplasmic reticulum stress is also linked to ischemic injury. ... -
The effects of blood–brain barrier disruption on glial cell function in multiple sclerosis: figure 1
McQuaid, Stephen; Cunnea, Paula; McMahon, Jill; Fitzgerald, Una (Portland Press Ltd., 2009-02-01)Dysfunction of the BBB (blood-brain barrier) is a major hallmark of MS (multiple sclerosis). Studies in our laboratories over the last decade have shown that increased 131313 permeability is associated with decreased ...