Browsing by Subject "pc12 cells"
Now showing items 1-3 of 3
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Hspb1 facilitates erk-mediated phosphorylation and degradation of bim to attenuate endoplasmic reticulum stress-induced apoptosis
(Springer Nature, 2017-08-31)BIM, a pro-apoptotic BH3-only protein, is a key regulator of the intrinsic (or mitochondrial) apoptosis pathway. Here, we show that BIM induction by endoplasmic reticulum (ER) stress is suppressed in rat PC12 cells ... -
Nerve growth factor blocks thapsigargin-induced apoptosis at the level of the mitochondrionviaregulation of bim
(Wiley-Blackwell, 2008-02-06)This study examined how the neurotrophin, nerve growth factor (NGF), protects PC12 cells against endoplasmic reticulum (ER) stress-induced apoptosis. ER stress was induced using thapsigargin (TG) that inhibits the ... -
Regulation of apoptosis by heat shock proteins
(Wiley-Blackwell, 2014-05-01)