Browsing by Subject "low-back-pain"

Now showing items 1-9 of 9

    • Assessing methods to specify the target difference for a randomised controlled trial: delta (difference elicitation in trials) review 

      Cook, Jonathan; Hislop, Jennifer; Adewuyi, Temitope; Harrild, Kirsten; Altman, Douglas; Ramsay, Craig; Fraser, Cynthia; Buckley, Brian; Fayers, Peter; Harvey, Ian; Briggs, Andrew; Norrie, John; Fergusson, Dean; Ford, Ian; Vale, Luke (National Institute for Health Research, 2014-01-01)
      Background: The randomised controlled trial (RCT) is widely considered to be the gold standard study for comparing the effectiveness of health interventions. Central to the design and validity of a RCT is a calculation of ...

    • Chronic pain in irish prison officers: profile and predictors of pain-related disability and depression 

      Costello, Elaine; Bogue, John E.; Sarma, Kiran; McGuire, Brian E. (Oxford University Press (OUP), 2015-12-01)
      Objective. International research has consistently found increased risk for physical health and psychological difficulties among prison officers including elevated risk of assault resulting in acute pain. This study ...

    • Gene expression profiling identifies interferon signalling molecules and igfbp3 in human degenerative annulus fibrosus 

      Kazezian, Zepur; Gawri, Rahul; Haglund, Lisbet; Ouellet, Jean; Mwale, Fackson; Tarrant, Finbarr; O’Gaora, Peadar; Pandit, Abhay; Alini, Mauro; Grad, Sibylle (Springer Nature, 2015-10-22)
      Low back pain is a major cause of disability especially for people between 20 and 50 years of age. As a costly healthcare problem, it imposes a serious socio-economic burden. Current surgical therapies fail to replace the ...

    • Offspring of parents with chronic pain 

      Higgins, Kristen S.; Birnie, Kathryn A.; Chambers, Christine T.; Wilson, Anna C.; Caes, Line; Clark, Alexander J.; Lynch, Mary; Stinson, Jennifer; Campbell-Yeo, Marsha (Ovid Technologies (Wolters Kluwer Health), 2015-11-01)
      Offspring of parents with chronic pain may be at risk for poorer outcomes than offspring of healthy parents. The objective of this research was to provide a comprehensive mixed-methods systematic synthesis of all available ...

    • Pretreatment anxiety and pain acceptance are associated with response to trigger point injection therapy for chronic myofascial pain 

      Healy, Gerard M.; Finn, David P.; O'Gorman, David A.; Maharaj, Chris; Raftery, Miriam; Ruane, Nancy; Mitchell, Caroline; Sarma, Kiran; Bohacek, Marek; McGuire, Brian E. (Oxford University Press (OUP), 2015-10-01)
      Background and AimThis study examined the psychosocial profile of patients who responded or did not respond to trigger point injection therapy for chronic myofascial pain. MethodsSeventy one patients with a diagnosis of ...

    • The 100 classic papers of orthopaedic surgery: a bibliometric analysis 

      Kelly, J. C.; Glynn, R. W.; O'Briain, D. E.; Felle, P.; McCabe, J. P. (British Editorial Society of Bone & Joint Surgery, 2010-09-30)
      The credibility and creativity of an author may be gauged by the number of scientific papers he or she has published, as well as the frequency of citations of a particular paper reflecting the impact of the data on the ...

    • The comet handbook: version 1.0 

      Williamson, Paula R.; Altman, Douglas G.; Bagley, Heather; Barnes, Karen L.; Blazeby, Jane M.; Brookes, Sara T.; Clarke, Mike; Gargon, Elizabeth; Gorst, Sarah; Harman, Nicola; Kirkham, Jamie J.; McNair, Angus; Prinsen, Cecilia A. C.; Schmitt, Jochen; Terwee, Caroline B.; Young, Bridget (Springer Nature, 2017-06-01)
      The selection of appropriate outcomes is crucial when designing clinical trials in order to compare the effects of different interventions directly. For the findings to influence policy and practice, the outcomes need to ...

    • The development of translational biomarkers as a tool for improving the understanding, diagnosis and treatment of chronic neuropathic pain 

      Buckley, David A.; Jennings, Elaine M.; Burke, Nikita N.; Roche, Michelle; McInerney, Veronica; Wren, Jonathan D.; Finn, David P.; McHugh, Patrick C. (Springer Nature, 2017-03-30)
      Chronic neuropathic pain (CNP) is one of the most significant unmet clinical needs in modern medicine. Alongside the lack of effective treatments, there is a great deficit in the availability of objective diagnostic methods ...

    • Work-related musculoskeletal disorders among irish farm operators 

      Osborne, Aoife; Blake, Catherine; Meredith, David; Kinsella, Anne; Phelan, James; McNamara, John; Cunningham, Caitriona (Wiley-Blackwell, 2012-07-10)