Browsing by Subject "interleukin-10"
Now showing items 1-5 of 5
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Biomaterial constructs for delivery of multiple therapeutic genes: a spatiotemporal evaluation of efficacy using molecular beacons
(Public Library of Science (PLoS), 2013-06-03)Gene therapy is emerging as a potential therapeutic approach for cardiovascular pathogenesis. An appropriate therapy may require multiple genes to enhance therapeutic outcome by modulating inflammatory response and ... -
Gene therapy approaches to prevent corneal graft rejection: where do we stand?
(S. Karger AG, 2013-01-01) -
Role of lentivirus-mediated overexpression of programmed death-ligand 1 on corneal allograft survival
(Wiley-Blackwell, 2012-02-02)To investigate the role of lentivirus-mediated overexpression of programmed death-ligand 1 (PD-L1) on rat corneal allograft survival. A fully allogeneic rat cornea transplant model was used for in vivo studies. Lentiviral ... -
Vil-10-overexpressing human mscs modulate naïve and activated t lymphocytes following induction of collagenase-induced osteoarthritis
(Springer Nature, 2016-05-18)Background: Recent efforts in osteoarthritis (OA) research have highlighted synovial inflammation and involvement of immune cells in disease onset and progression. We sought to establish the in-vivo immune response in ... -
Vitamin d receptor variants and uncontrolled asthma
(Edra SpA, 2018-01-01)Background. Asthma is a common childhood respiratory disease, affecting around 20% of Irish children. In other populations, vitamin D receptor (VDR) polymorphisms have been associated with asthma risk. We aimed to investigate ...