Browsing by Subject "indomethacin"
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Amorphous solid dispersions of sulfonamide/soluplus® and sulfonamide/pvp prepared by ball milling
(American Association of Pharmaceutical Scientists (AAPS), 2013-02-07)The aim of this paper is to investigate the physicochemical properties of binary amorphous dispersions of poorly soluble sulfonamide/polymeric excipient prepared by ball milling. The sulfonamides selected were sulfathiazole ... -
Investigation of the capacity of low glass transition temperature excipients to minimize amorphization of sulfadimidine on comilling
(American Chemical Society (ACS), 2013-01-07)The coprocessing of active pharmaceutical ingredient (API) with an excipient which has a high glass transition temperature (T-g) is a recognized strategy to stabilize the amorphous form of a drug. This work investigates ...