Browsing by Subject "gene-expression"
Now showing items 1-20 of 81
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17 -estradiol treatment decreases steroidogenic enzyme messenger ribonucleic acid levels in the rainbow trout testis
(The Endocrine Society, 2001-05-01)In fish, estrogens are well known for their involvement in ovarian differentiation and have been shown to be very potent feminizing agents when administrated in vivo during early development. However, the mechanism of ... -
A lifetime of stress: atf6 in development and homeostasis
(Springer Nature, 2018-05-25)Background: Activating transcription factor 6 (ATF6) is an endoplasmic reticulum (ER)-localised protein and member of the leucine zipper family of transcription factors. Best known for its role in transducing signals linked ... -
a novel mechanism, linked to cell density, largely controls cell division in synechocystis
(American Society of Plant Biologists (ASPB), 2017-06-23)Many studies have investigated the various genetic and environmental factors regulating cyanobacterial growth. Here, we investigated the growth and metabolism of Synechocystis sp. PCC 6803 under different nitrogen sources, ... -
Adrb3 adrenergic receptor is a key regulator of human myometrial apoptosis and inflammation during chorioamnionitis1
(Oxford University Press (OUP), 2008-03-01)The pathophysiology underlying preterm labor triggered by inflammatory conditions such as chorioamnionitis remains largely unclear. It has already been suggested that beta-3 adrenergic (ADRB3) agonists might be of interest ... -
Alterations in hepatic mirna expression during negative energy balance in postpartum dairy cattle
(Springer Nature, 2014-01-01)Background: Negative energy balance (NEB), an altered metabolic state, occurs in early postpartum dairy cattle when energy demands to support lactation exceed energy intake. During NEB the liver undergoes oxidative stress ... -
An atr‐dependent function for the ddx19 rna helicase in nuclear r‐loop metabolism
(EMBO, 2017-03-17)Coordination between transcription and replication is crucial in the maintenance of genome integrity. Disturbance of these processes leads to accumulation of aberrant DNA: RNA hybrids (R-loops) that, if unresolved, generate ... -
An essential role for coagulase instaphylococcus aureusbiofilm development reveals new therapeutic possibilities for device-related infections
(Oxford University Press (OUP), 2015-06-04)High-level resistance to antimicrobial drugs is a major factor in the pathogenesis of chronic Staphylococcus aureus biofilm-associated, medical device-related infections. Antimicrobial susceptibility analysis revealed that ... -
Arac-type regulator rbf controls the staphylococcus epidermidis biofilm phenotype by negatively regulating theicaadbcrepressor sarr
(American Society for Microbiology, 2016-08-08)Regulation of icaADBC-encoded polysaccharide intercellular adhesin (PIA)/poly-N-acetylglucosasmine (PNAG) production in staphylococci plays an important role in biofilm-associated medical-device-related infections. Here, ... -
Candidate pathways linking inducible nitric oxide synthase to a basal-like transcription pattern and tumor progression in human breast cancer
(Informa UK Limited, 2011-02-15)Inducible nitric oxide synthase (NOS2) is an inflammation responsive enzyme (EC 1.14.13.39) that is induced during acute and chronic inflammation and tissue injury as part of the host defense and wound healing process. ... -
Ceratopteris richardii (c-fern): a model for investigating adaptive modification of vascular plant cell walls
(Frontiers Media SA, 2013-01-01)Plant cell walls are essential for most aspects of plant growth, development, and survival, including cell division, expansive cell growth, cell-cell communication, biomechanical properties, and stress responses. Therefore, ... -
Clinical use of the oncotype dx genomic test to guide treatment decisions for patients with invasive breast cancer
(Dove Medical Press Ltd., 2017-05-01)Implementation of the Oncotype DX assay has led to a change in the manner in which chemotherapy is utilized in patients with early stage, estrogen receptor (ER)-positive, node-negative breast cancer; ensuring that patients ... -
Cmcgg methylation-independent parent-of-origin effects on genome-wide transcript levels in isogenic reciprocal f1 triploid plants
(Oxford University Press (OUP), 2013-11-07)Triploid F1 hybrids generated via reciprocal interploidy crosses between genetically distinct parental plants can display parent-of-origin effects on gene expression or phenotypes. Reciprocal triploid F1 isogenic plants ... -
Comparative rna expression analyses from small-scale, single-donor platelet samples1
(Wiley-Blackwell, 2006-02-01)Background: Comparisons of platelet RNAs could provide crucial information on platelet function, thrombopoiesis and the etiology of megakaryocyte (MK) or platelet disorders. Objectives: We developed a method for stringent ... -
Cross-feeding by bifidobacterium breve ucc2003 during co-cultivation with bifidobacterium bifidum prl2010 in a mucin-based medium
(Springer Nature, 2014-11-25)Background: Bifidobacteria constitute a specific group of commensal bacteria that commonly inhabit the mammalian gastrointestinal tract. Bifidobacterium breve UCC2003 was previously shown to utilize a variety of ... -
Differential response of mouse thymic epithelial cell types to ionizing radiation-induced dna damage
(Frontiers Media SA, 2017-04-13)Thymic epithelial cells (TECs) are the main components of the thymic stroma that support and control T-cell development. Preparative regimens using DNA-damaging agents, such as total body irradiation and/or chemotherapeutic ... -
Differential β3and β1integrin expression in bone marrow and cortical bone of estrogen deficient rats
(Wiley-Blackwell, 2015-06-03) -
Dissecting the pre-placodal transcriptome to reveal presumptive direct targets of six1 and eya1 in cranial placodes
(eLife Sciences Organisation, Ltd., 2016-08-31)The pre-placodal ectoderm, marked by the expression of the transcription factor Six1 and its co-activator Eya1, develops into placodes and ultimately into many cranial sensory organs and ganglia. Using RNA-Seq in Xenopus ... -
Effect of level of eicosapentaenoic acid on the transcriptional regulation of δ-9 desaturase using a novel in vitro bovine intramuscular adipocyte cell culture model
(Cambridge University Press (CUP), 2009-02-06)Ruminant fat is often perceived as having a negative impact on human health; however, the composition of the fat is under complex biochemical control and can be improved through strategic manipulation of the animal's diet. ... -
Effects of combined progesterone and 17β-estradiol treatment on the transcriptome of cultured human myometrial smooth muscle cells
(American Physiological Society, 2015-11-03)A transcriptomic analysis of cultured human uterine smooth muscle cells (hUtSMCs) was performed to examine gene expression profiles in smooth muscle in an environment containing the two major steroid hormones that regulate ... -
Effects of repeated cycles of acid challenge and growth on the phenotype and virulence ofsalmonella enterica
(Wiley-Blackwell, 2008-11-01)Aims: The aim of the study was to investigate how stresses like low pH, which may be encountered in farms or food preparation premises, shape populations of Salmonella enterica by the selection of stress-resistant ...