Browsing by Subject "fission yeast"
Now showing items 1-7 of 7
-
Centromere sliding on a mammalian chromosome
(Springer Nature, 2014-11-21)The centromere directs the segregation of chromosomes during mitosis and meiosis. It is a distinct genetic locus whose identity is established through epigenetic mechanisms that depend on the deposition of centromere-specific ... -
Patronus1 is expressed in meiotic prophase i to regulate centromeric cohesion in arabidopsis and shows synthetic lethality with osd1
(Springer Nature, 2015-08-14)Background: Retention of sister centromere cohesion during meiosis I and its dissolution at meiosis II is necessary for balanced chromosome segregation and reduction of chromosome number. PATRONUS1 (PANS1) has recently ... -
Repression of g1/s transcription is mediated via interaction of the gtb motifs of nrm1 and whi5 with swi6
(American Society for Microbiology, 2013-02-04)In Saccharomyces cerevisiae, G(1)/S transcription factors MBF and SBF regulate a large family of genes important for entry to the cell cycle and DNA replication and repair. Their regulation is crucial for cell viability, ... -
Roles of vertebrate smc5 in sister chromatid cohesion and homologous recombinational repair
(American Society for Microbiology, 2011-01-18)The structural maintenance of chromosomes (Smc) family members Smc5 and Smc6 are both essential in budding and fission yeasts. Yeast smc5/6 mutants are hypersensitive to DNA damage, and Smc5/6 is recruited to HO-induced ... -
Sister chromatid cohesion and genome stability in vertebrate cells
(Portland Press Ltd., 2003-02-01)For successful eukaryotic mitosis, sister chromatid pairs remain linked after replication until their kinetochores have been attached to opposite spindle poles by microtubules. This linkage is broken at the metaphase-anaphase ... -
Structure-function analysis of hmo1 unveils an ancestral organization of hmg-box factors involved in ribosomal dna transcription from yeast to human
(Oxford University Press (OUP), 2013-09-09)Ribosome biogenesis is a major metabolic effort for growing cells. In Saccharomyces cerevisiae, Hmo1, an abundant high-mobility group box protein (HMGB) binds to the coding region of the RNA polymerase I transcribed ribosomal ... -
The nse2/mms21 sumo ligase of the smc5/6 complex in the maintenance of genome stability
(Wiley-Blackwell, 2011-05-04)