Browsing by Subject "fibrosis"

Now showing items 1-3 of 3

    • A collagen-based scaffold delivering exogenous microrna-29b to modulate extracellular matrix remodeling 

      Monaghan, Michael; Browne, Shane; Schenke-Layland, Katja; Pandit, Abhay (Elsevier BV, 2014-04-01)
      Directing appropriate extracellular matrix remodeling is a key aim of regenerative medicine strategies. Thus, antifibrotic interfering RNA (RNAi) therapy with exogenous microRNA (miR)-29B was proposed as a method to modulate ...

    • Osteopontin is upregulated in human and murine acute schistosomiasis mansoni 

      Pereira, Thiago Almeida; Syn, Wing-Kin; Amâncio, Frederico Figueiredo; Cunha, Pedro Henrique Diniz; Caporali, Julia Fonseca Morais; Trindade, Guilherme Vaz de Melo; Santos, Elisângela Trindade; Souza, Márcia Maria; Andrade, Zilton Araújo; Witek, Rafal P; Secor, William Evan; Pereira, Fausto Edmundo Lima; Lambertucci, José Roberto; Diehl, Anna Mae (Public Library of Science (PLoS), 2016-10-18)
      Background Symptomatic acute schistosomiasis mansoni is a systemic hypersensitivity reaction against the migrating schistosomula and mature eggs after a primary infection. The mechanisms involved in the pathogenesis of ...

    • Risk of liver disease in methotrexate treated patients 

      Conway, Richard; Carey, John J (Baishideng Publishing Group Inc., 2017-01-01)
      Methotrexate is the first line drug treatment for a number of rheumatic and non-rheumatic diseases. It is effective in controlling disease activity and preventing disease-related damage, and significantly cheaper than many ...