Browsing by Subject "Integrin"
Now showing items 1-2 of 2
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Differential β3 and β1 integrin expression in bone marrow and cortical bone of estrogen deficient rats
(Wiley, 2015-08-12)Integrin-based (beta(3)) attachments to the extracellular matrix (ECM) on osteocyte cell processes have recently been proposed to play an important role in facilitating osteocyte mechanosensation. However, it is not yet ... -
Estrogen withdrawal in osteocytes results in altered integrin function, primary cilium elongation, and increased pro-osteoclastogenic signalling
(NUI Galway, 2020-06-28)Osteocytes are the main mechanosensitive cells within bone. They detect changes in the mechanical environment and transduce them into biochemical responses (RANKL, OPG, and sclerostin) that regulate bone remodelling by ...