Browsing by Author "Stocca, Alessia"
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Bone marrow-derived mesenchymal stem cells have innate procoagulant activity and cause microvascular obstruction following intracoronary delivery: amelioration by antithrombin therapy
Gleeson, Birgitta M.; Martin, Kenneth; Ali, Mohammed T.; Kumar, Arun H. S.; Pillai, M. Gopala-Krishnan; Kumar, Sujith P. G.; O'Sullivan, John F.; Whelan, Derek; Stocca, Alessia; Khider, Wisam; Barry, Frank P.; O'Brien, Timothy; Caplice, Noel M. (Wiley-Blackwell, 2015-06-04)Mesenchymal stem cells (MSCs) are currently under investigation as tools to preserve cardiac structure and function following acute myocardial infarction (AMI). However, concerns have emerged regarding safety of acute ... -
Mesenchymal stem cell survival in the infarcted heart is enhanced by lentivirus vector-mediated heat shock protein 27 expression
McGinley, Lisa M.; McMahon, Jill; Stocca, Alessia; Duffy, Aoife; Flynn, Aidan; O'Toole, Daniel; O'Brien, Timothy (Mary Ann Liebert Inc, 2013-10-01)Mesenchymal stem cell (MSC) therapy offers the potential to promote recovery after myocardial infarction (MI). However, therapeutic efficacy may be limited by poor survival and retention of transplanted cells. A combination ...