Browsing by Author "Newell, John"
Now showing items 1-20 of 60
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A cluster randomised controlled trial evaluating the effectiveness of a structured pulmonary rehabilitation education programme for improving the health status of people with chronic obstructive pulmonary disease (copd): the prince study protocol
Murphy, Kathy; Casey, Dympna; Devane, Declan; Cooney, Adeline; McCarthy, Bernard; Mee, Lorraine; Nichulain, Martina; Murphy, Andrew W; Newell, John; O' Shea, Eamon (Springer Nature, 2011-01-18)Background: A key strategy in improving care for people with chronic obstructive pulmonary disease (COPD) is the provision of pulmonary rehabilitation programmes. Pulmonary rehabilitation programmes have been successful ... -
A germline mutation in the brca13’utr predicts stage iv breast cancer
Dorairaj, Jemima J; Salzman, David W; Wall, Deirdre; Rounds, Tiffany; Preskill, Carina; Sullivan, Catherine AW; Lindner, Robert; Curran, Catherine; Lezon-Geyda, Kim; McVeigh, Terri; Harris, Lyndsay; Newell, John; Kerin, Michael J; Wood, Marie; Miller, Nicola; Weidhaas, Joanne B (Springer Nature, 2014-06-10)Background: A germline, variant in the BRCA1 3'UTR (rs8176318) was previously shown to predict breast and ovarian cancer risk in women from high-risk families, as well as increased risk of triple negative breast cancer. ... -
A randomised controlled trial of an exercise plus behaviour change intervention in people with multiple sclerosis: the step it up study protocol
Coote, Susan; Gallagher, Stephen; Msetfi, Rachel; Larkin, Aidan; Newell, John; Motl, Robert W; Hayes, Sara (Springer Nature, 2014-12-01)Background: Exercise has consistently yielded short-term, positive effects on health outcomes in people with multiple sclerosis (MS). However, these effects have not been maintained in the long-term. Behaviour change ... -
An evaluation of cro� myaction community lifestyle modification programme compared to standard care to reduce progression to diabetes/pre-diabetes in women with prior gestational diabetes mellitus (gdm): study protocol for a randomised controlled trial
Infanti, Jennifer J; Dunne, Fidelma P; O�Dea, Angela; Gillespie, Paddy; Gibson, Irene; Glynn, Liam G; Noctor, Eoin; Newell, John; McGuire, Brian E (Springer Nature, 2013-01-01)Background: Universal screening using the International Association of Diabetes and Pregnancy Study Groups (IADPSG) criteria has identified a prevalence of gestational diabetes mellitus (GDM) of 12.4% in women living in ... -
Bayesian imputation of right censored data in time-to-event studies
Moghaddam, Shirin (NUI Galway, 2018-03-20)In time-to-event studies subjects are followed until the event of interest has happened. Subjects who do not experience the event are referred to as censored. Due to censoring, methods of plotting individual survival ... -
Bilateral breast cancer: analysis of incidence, outcome, survival and disease characteristics
Kheirelseid, Elrasheid A. H.; Jumustafa, Hanzali; Miller, Nicola; Curran, Catherine; Sweeney, Karl; Malone, Carmel; McLaughlin, Ray; Newell, John; Kerin, Michael J. (Springer Nature, 2010-07-28)There has been conflicting evidence on the impact of bilateral breast cancer (BBC) on the survival and management of patients. The objectives of this study were to address the incidence of BBC and to investigate its ... -
Can the onset of type 2 diabetes be delayed by a group-based lifestyle intervention in women with prediabetes following gestational diabetes mellitus (gdm)? findings from a randomized control mixed methods trial
O’Dea, Angela; Tierney, Marie; McGuire, Brian E.; Newell, John; Glynn, Liam G.; Gibson, Irene; Noctor, Eoin; Danyliv, Andrii; Connolly, Susan B.; Dunne, Fidelma P. (Hindawi Limited, 2015-01-01)Objective. To evaluate a 12-week group-based lifestyle intervention programme for women with prediabetes following gestational diabetes (GDM). Design. A two-group, mixed methods randomized controlled trial in which 50 women ... -
A cluster randomised controlled trial evaluating the effectiveness of a structured pulmonary rehabilitation education programme for improving the health status of people with chronic obstructive pulmonary disease (COPD): The PRINCE Study protocol.
Murphy, Kathy; Casey, Dympna; Devane, Declan; Cooney, Adeline; McCarthy, Bernard; Mee, Lorraine; Ní Chúlain, Martina; Murphy, Andrew W.; Newell, John; O'Shea, Eamon (BioMed Central, 2011-01-18)A key strategy in improving care for people with chronic obstructive pulmonary disease (COPD) is the provision of pulmonary rehabilitation programmes. Pulmonary rehabilitation programmes have been successful in improving ... -
Comparing the clinical-effectiveness and cost-effectiveness of an internet-delivered Acceptance and Commitment Therapy (ACT) intervention with a waiting list control among adults with chronic pain: study protocol for a randomised controlled trial
Hayes, Sara; Hogan, Michael; Dowd, Haulie; Doherty, Edel; O'Higgins, Siobhan; Nic Gabhainn, Saoirse; MacNeela, Padraig; Murphy, Andrew W.; Kropmans, Thomas; O'Neill, Ciaran; Newell, John; McGuire, Brian E. (BMJ Publishing Group, 2014-07-02)Internet-delivered psychological interventions among people with chronic pain have the potential to overcome environmental and economic barriers to the provision of evidence-based psychological treatment in the Irish health ... -
Critical difference and biological variation in biomarkers of oxidative stress and nutritional status in athletes
Lewis, Nathan A.; Newell, John; Burden, Richard; Howatson, Glyn; Pedlar, Charles R. (Public Library of Science (PLoS), 2016-03-01)The longitudinal monitoring of oxidative stress (OS) in athletes may enable the identification of fatigued states and underperformance. The application of OS biomarker monitoring programs in sport are hindered by reliability ... -
Derivative Estimation in Noisy Data; an Additive Penalty P-Spline Approach
Simpkin, Andrew (2010-12-20)In many situations it is of primary interest to estimate the rate of change of the relationship between response and explanatory variables. In this thesis derivative estimation using spline smoothing is explored. A review ... -
Effect of exercising at minimum recommendations of the multiple sclerosis exercise guideline combined with structured education or attention control education – secondary results of the step it up randomised controlled trial
Coote, Susan; Uszynski, Marcin; Herring, Matthew P.; Hayes, Sara; Scarrott, Carl; Newell, John; Gallagher, Stephen; Larkin, Aidan; Motl, Robert W (Springer Nature, 2017-06-24)Background: Recent exercise guidelines for people with multiple sclerosis (MS) recommend a minimum of 30 min moderate intensity aerobic exercise and resistance exercise twice per week. This trial compared the secondary ... -
Effect of tailored practice and patient care plans on secondary prevention of heart disease in general practice: cluster randomised controlled trial.
Murphy, Andrew W.; Byrne, Molly; Newell, John (2009)Objective To test the effectiveness of a complex intervention designed, within a theoretical framework, to improve outcomes for patients with coronary heart disease. Design Cluster randomised controlled multicentre trial. ... -
Effectiveness of a cognitive behavioural therapy-based rehabilitation programme (progressive goal attainment program) for patients who are work-disabled due to back pain: study protocol for a multicentre randomised controlled trial
Raftery, Miriam N; Murphy, Andrew W; O’Shea, Eamon; Newell, John; McGuire, Brian E (Springer Nature, 2013-01-01)Background: Psychologically informed rehabilitation programmes such as the Progressive Goal Attainment Program (PGAP) have the potential to address pain-related disability by targeting known psychological factors that ... -
Estimating average attributable fractions with confidence intervals for cohort and case control studies
Ferguson, John; Alvarez-Iglesias, Alberto; Newell, John; Hinde, John; O’Donnell, Martin (SAGE Publications, 2016-06-24)Chronic diseases tend to depend on a large number of risk factors, both environmental and genetic. Average attributable fractions were introduced by Eide and Gefeller as a way of partitioning overall disease burden into ... -
An evaluation of MyAction, a community-based lifestyle and medical risk factor modification programme, in women with prior gestational diabetes mellitus: study protocol for a randomised controlled trial
Infanti, Jennifer J.; Dunne, Fidelma P.; Gillespie, Paddy; Glynn, Liam G.; Noctor, Eoin; Newell, John; McGuire, Brian E.; O'Dea, Angela (BioMed Central, 2013-05-02)Universal screening using the International Association of Diabetes and Pregnancy Study Groups (IADPSG) criteria has identified a prevalence of gestational diabetes mellitus (GDM) of 12.4% in women living in Ireland. Women ... -
Extending the linear mixed modelling framework for method comparison studies involving functional responses with applications in elite sports
Das, Kishor (NUI Galway, 2023-01-10)A method comparison study compares two or more different methods measuring some quantity of interest and the aim is to determine the level of agreement between the methods. Most of the methodological developments in this ... -
Extensions and Applications of Survival Trees in Medical Data
Alvarez-Iglesias, Alberto (2012-09-17)Survival trees are a non-parametric modeling strategy that can be included in the area of statistical modeling. These type of models can be used as an alternative to Cox proportional hazards models for the analysis of ... -
Feasibility of a physical activity programme embedded into the daily lives of older adults living in nursing homes: protocol for a randomised controlled pilot feasibility study
Barrett, Eva; Gillespie, Paddy; Newell, John; Casey, Dympna (BMC, 2018-04-20)Background: Older adults living in nursing homes spend the majority of their time inactive. The associated levels of chronic disease places an increasing burden on healthcare systems. Physical activity (PA) interventions ... -
Feasibility, acceptability and uptake rates of gestational diabetes mellitus screening in primary care vs secondary care: findings from a randomised controlled mixed methods trial
Tierney, Marie; O’Dea, Angela; Danyliv, Andriy; Glynn, Liam G.; McGuire, Brian E.; Carmody, Louise A; Newell, John; Dunne, Fidelma P. (Springer Nature, 2015-08-05)Aims/hypothesis It is postulated that uptake rates for gestational diabetes mellitus (GDM) screening would be improved if offered in a setting more accessible to the patient. The aim of this study was to evaluate the ...