Browsing by Author "McDonald, C."

Now showing items 1-11 of 11

    • Applying neuroimaging to detect neuroanatomical dysconnectivity in psychosis 

      O'Donoghue, S.; Cannon, D. M.; Perlini, C.; Brambilla, P.; McDonald, C. (Cambridge University Press (CUP), 2015-02-12)
      This editorial discusses the application of a novel brain imaging analysis technique in the assessment of neuroanatomical dysconnectivity in psychotic illnesses. There has long been a clinical interest in psychosis as a ...

    • Associations between psychosis endophenotypes across brain functional, structural, and cognitive domains 

      Blakey, R.; Ranlund, S.; Zartaloudi, E.; Cahn, W.; Calafato, S.; Colizzi, M.; Crespo-Facorro, B.; Daniel, C.; Díez-Revuelta, Á.; Di Forti, M.; Iyegbe, C.; Jablensky, A.; Jones, R.; Hall, M.-H.; Kahn, R.; Kalaydjieva, L.; Kravariti, E.; Lin, K.; McDonald, C.; McIntosh, A. M.; Picchioni, M.; Powell, J.; Presman, A.; Rujescu, D.; Schulze, K.; Shaikh, M.; Thygesen, J. H.; Toulopoulou, T.; Van Haren, N.; Van Os, J.; Walshe, M.; Murray, R. M.; Bramon, E.; , (Cambridge University Press (CUP), 2017-11-02)
      Background. A range of endophenotypes characterise psychosis, however there has been limited work understanding if and how they are inter-related. Methods. This multi-centre study includes 8754 participants: 2212 people ...

    • Authors' reply 

      McDonald, C. (Royal College of Psychiatrists, 2006-04-01)

    • Clinical symptomatology and the psychosis risk gene znf804a 

      Cummings, E.; Donohoe, G.; McDonald, C.; Dinan, T.G.; O'Neill, F.A.; O'Callaghan, E.; Waddington, J.L.; Murphy, K.C.; Gill, M.; Morris, Derek W.; Corvin, A. (Elsevier BV, 2010-09-01)

    • Effectiveness of a low support, remotely accessible, cognitive remediation training programme for chronic psychosis: cognitive, functional and cortical outcomes from a single blind randomised controlled trial 

      Donohoe, G.; Dillon, R.; Hargreaves, A.; Mothersill, O.; Castorina, M.; Furey, E.; Fagan, A. J.; Meaney, J. F.; Fitzmaurice, B.; Hallahan, B.; McDonald, C.; Wykes, T.; Corvin, A.; Robertson, I. H. (Cambridge University Press (CUP), 2017-09-21)
      Background. Cognitive remediation (CR) training has emerged as a promising approach to improving cognitive deficits in schizophrenia and related psychosis. The limited availability of psychological services for psychosis ...

    • New insights into the endophenotypic status of cognition in bipolar disorder: genetic modelling study of twins and siblings 

      Georgiades, A.; Rijsdijk, F.; Kane, F.; Rebollo-Mesa, I.; Kalidindi, S.; Schulze, K. K.; Stahl, D.; Walshe, M.; Sahakian, B. J.; McDonald, C.; Hall, M.-H.; Murray, R. M.; Kravariti, E. (Royal College of Psychiatrists, 2016-03-17)
      Background Twin studies have lacked statistical power to apply advanced genetic modelling techniques to the search for cognitive endophenotypes for bipolar disorder. Aims To quantify the shared genetic variability between ...

    • Positive symptoms associate with cortical thinning in the superior temporal gyrus via the enigma schizophrenia consortium 

      Walton, E.; Hibar, D. P.; van Erp, T. G. M.; Potkin, S. G.; Roiz-Santiañez, R.; Crespo-Facorro, B.; Suarez-Pinilla, P.; Van Haren, N. E. M.; de Zwarte, S. M. C.; Kahn, R. S.; Cahn, W.; Doan, N. T.; Jørgensen, K. N.; Gurholt, T. P.; Agartz, I.; Andreassen, O. A.; Westlye, L. T.; Melle, I.; Berg, A. O.; Mørch-Johnsen, L.; Faerden, A.; Flyckt, L.; Fatouros-Bergman, H.; Jönsson, E. G.; Hashimoto, R.; Yamamori, H.; Fukunaga, M.; Preda, A.; De Rossi, P.; Piras, F.; Banaj, N.; Ciullo, V.; Spalletta, G.; Gur, R. E.; Gur, R. C.; Wolf, D. H; Satterthwaite, T. D.; Beard, L. M.; Sommer, I. E.; Koops, S.; Gruber, O.; Richter, A.; Krämer, B.; Kelly, S.; Donohoe, G.; McDonald, C.; Cannon, D. M.; Corvin, A.; Gill, M.; Di Giorgio, A.; Bertolino, A.; Lawrie, S.; Nickson, T.; Whalley, H. C.; Neilson, E.; Calhoun, V. D.; Thompson, P. M.; Turner, J. A.; Ehrlich, S.; , (Wiley-Blackwell, 2017-03-29)
      ObjectiveBased on the role of the superior temporal gyrus (STG) in auditory processing, language comprehension and self-monitoring, this study aimed to investigate the relationship between STG cortical thickness and positive ...

    • Prefrontal cortical thinning links to negative symptoms in schizophrenia via the enigma consortium 

      Walton, E.; Hibar, D. P.; van Erp, T. G. M.; Potkin, S. G.; Roiz-Santiañez, R.; Crespo-Facorro, B.; Suarez-Pinilla, P.; van Haren, N. E. M.; de Zwarte, S. M. C.; Kahn, R. S.; Cahn, W.; Doan, N. T.; Jørgensen, K. N.; Gurholt, T. P.; Agartz, I.; Andreassen, O. A.; Westlye, L. T.; Melle, I.; Berg, A. O.; Morch-Johnsen, L.; Færden, A.; Flyckt, L.; Fatouros-Bergman, H.; Jönsson, E. G.; Hashimoto, R.; Yamamori, H.; Fukunaga, M.; Jahanshad, N.; De Rossi, P.; Piras, F.; Banaj, N.; Spalletta, G.; Gur, R. E.; Gur, R. C.; Wolf, D. H.; Satterthwaite, T. D.; Beard, L. M.; Sommer, I. E.; Koops, S.; Gruber, O.; Richter, A.; Krämer, B.; Kelly, S.; Donohoe, G.; McDonald, C.; Cannon, D. M.; Corvin, A.; Gill, M.; Di Giorgio, A.; Bertolino, A.; Lawrie, S.; Nickson, T.; Whalley, H. C.; Neilson, E.; Calhoun, V. D.; Thompson, P. M.; Turner, J. A.; Ehrlich, S.; , (Cambridge University Press (CUP), 2017-05-26)
      Background. Our understanding of the complex relationship between schizophrenia symptomatology and etiological factors can be improved by studying brain-based correlates of schizophrenia. Research showed that impairments ...

    • The impact of cacna1c gene, and its epistasis with znf804a, on white matter microstructure in health, schizophrenia and bipolar disorder1 

      Mallas, E.; Carletti, F.; Chaddock, C. A.; Shergill, S.; Woolley, J.; Picchioni, M. M.; McDonald, C.; Toulopoulou, T.; Kravariti, E.; Kalidindi, S.; Bramon, E.; Murray, R.; Barker, G. J.; Prata, D. P. (Wiley-Blackwell, 2016-11-29)
      Genome-wide studies have identified allele A (adenine) of single nucleotide polymorphism (SNP) rs1006737 of the calcium-channel CACNA1C gene as a risk factor for both schizophrenia (SZ) and bipolar disorder (BD) as well ...

    • White matter microstructural abnormalities in families multiply affected with bipolar i disorder: a diffusion tensor tractography study 

      Emsell, L.; Chaddock, C.; Forde, N.; Van Hecke, W.; Barker, G. J.; Leemans, A.; Sunaert, S.; Walshe, M.; Bramon, E.; Cannon, D.; Murray, R.; McDonald, C. (Cambridge University Press (CUP), 2013-11-27)
      Background. White matter (WM) abnormalities are proposed as potential endophenotypic markers of bipolar disorder (BD). In a diffusion tensor imaging (DTI) voxel-based analysis (VBA) study of families multiply affected with ...

    • White matter microstructural impairments and genetic liability to familial bipolar i disorder 

      Chaddock, C. A.; Barker, G. J.; Marshall, N.; Schulze, K.; Hall, M. H.; Fern, A.; Walshe, M.; Bramon, E.; Chitnis, X. A.; Murray, R.; McDonald, C. (Royal College of Psychiatrists, 2009-05-28)
      Background Subtle abnormalities in frontal white matter have been reported in bipolar disorder. Aims To assess whether impaired integrity of white matter tracts is associated with bipolar disorder and genetic liability for ...