Browsing by Author "Houston, Aileen"
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Targeting the ep1 receptor reduces fas ligand expression and increases the antitumor immune response in anin vivomodel of colon cancer
O'Callaghan, Grace; Ryan, Aideen; Neary, Peter; O'Mahony, Caitlin; Shanahan, Fergus; Houston, Aileen (Wiley-Blackwell, 2013-03-04)Despite studies demonstrating that inhibition of cyclooxygenase-2 (COX-2)-derived prostaglandin E2 (PGE2) has significant chemotherapeutic benefits in vitro and in vivo, inhibition of COX enzymes is associated with serious ...