Browsing by Author "Gillihan, Ryan"
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Different mechanisms for resistance to trastuzumab versus lapatinib in her2- positive breast cancers - role of estrogen receptor and her2 reactivation
Wang, Yen-Chao; Morrison, Gladys; Gillihan, Ryan; Guo, Jun; Ward, Robin M; Fu, Xiaoyong; Botero, Maria F; Healy, Nuala A; Hilsenbeck, Susan G; Phillips, Gail Lewis; Chamness, Gary C; Rimawi, Mothaffar F; Osborne, C Kent; Schiff, Rachel (Springer Nature, 2011-11-28)Introduction: The human epidermal growth factor receptor 2 (HER2)-targeted therapies trastuzumab (T) and lapatinib (L) show high efficacy in patients with HER2-positive breast cancer, but resistance is prevalent. Here we ...