Browsing by Author "Curley, Gerard"
Now showing items 1-5 of 5
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Bench-to-bedside review: carbon dioxide
Curley, Gerard; Laffey, John G; Kavanagh, Brian P (Springer Nature, 2010-01-01)Carbon dioxide is a waste product of aerobic cellular respiration in all aerobic life forms. PaCO(2) represents the balance between the carbon dioxide produced and that eliminated. Hypocapnia remains a common and generally ... -
Can 'permissive' hypercapnia modulate the severity of sepsis-induced ali/ards?
Curley, Gerard; Hayes, Mairead; Laffey, John G (Springer Nature, 2011-01-01) -
Clinical review: stem cell therapies for acute lung injury/acute respiratory distress syndrome - hope or hype?
Hayes, Mairead; Curley, Gerard; Ansari, Bilal; Laffey, John G (Springer Nature, 2012-01-01)A growing understanding of the complexity of the pathophysiology of acute lung injury (ALI)/acute respiratory distress syndrome (ARDS), coupled with advances in stem cell biology, has led to a renewed interest in the ... -
Hypercapnia and acidosis in sepsis
Curley, Gerard; Contreras, Maya; Nichol, Alistair D.; Higgins, Brendan D.; Laffey, John G. (Ovid Technologies (Wolters Kluwer Health), 2010-02-01)Acute respiratory distress syndrome is a devastating disease that causes substantial morbidity and mortality. Mechanical ventilation can worsen lung injury, whereas ventilatory strategies that reduce lung stretch, resulting ... -
Investigation of the mechanisms of repair following Ventilator Induced Lung Injury and the potential for Mesenchymal Stem Cells to enhance the repair process
Curley, Gerard (2012-02-10)Introduction: ARDS is a syndrome of acute respiratory failure that presents with progressive arterial hypoxemia, dyspnea, and a marked increase in the work of breathing. Virtually all patients with ARDS receive mechanical ...