Browsing by Subject "population"

Now showing items 21-40 of 52

    • Genetic risk factors for ischaemic stroke and its subtypes (the metastroke collaboration): a meta-analysis of genome-wide association studies 

      Traylor, Matthew; Farrall, Martin; Holliday, Elizabeth G; Sudlow, Cathie; Hopewell, Jemma C; Cheng, Yu-Ching; Fornage, Myriam; Ikram, M Arfan; Malik, Rainer; Bevan, Steve; Thorsteinsdottir, Unnur; Nalls, Mike A; Longstreth, WT; Wiggins, Kerri L; Yadav, Sunaina; Parati, Eugenio A; DeStefano, Anita L; Worrall, Bradford B; Kittner, Steven J; Khan, Muhammad Saleem; Reiner, Alex P; Helgadottir, Anna; Achterberg, Sefanja; Fernandez-Cadenas, Israel; Abboud, Sherine; Schmidt, Reinhold; Walters, Matthew; Chen, Wei-Min; Ringelstein, E Bernd; O'Donnell, Martin; Ho, Weang Kee; Pera, Joanna; Lemmens, Robin; Norrving, Bo; Higgins, Peter; Benn, Marianne; Sale, Michele; Kuhlenbäumer, Gregor; Doney, Alexander S F; Vicente, Astrid M; Delavaran, Hossein; Algra, Ale; Davies, Gail; Oliveira, Sofia A; Palmer, Colin N A; Deary, Ian; Schmidt, Helena; Pandolfo, Massimo; Montaner, Joan; Carty, Cara; de Bakker, Paul I W; Kostulas, Konstantinos; Ferro, Jose M; van Zuydam, Natalie R; Valdimarsson, Einar; Nordestgaard, Børge G; Lindgren, Arne; Thijs, Vincent; Slowik, Agnieszka; Saleheen, Danish; Paré, Guillaume; Berger, Klaus; Thorleifsson, Gudmar; Hofman, Albert; Mosley, Thomas H; Mitchell, Braxton D; Furie, Karen; Clarke, Robert; Levi, Christopher; Seshadri, Sudha; Gschwendtner, Andreas; Boncoraglio, Giorgio B; Sharma, Pankaj; Bis, Joshua C; Gretarsdottir, Solveig; Psaty, Bruce M; Rothwell, Peter M; Rosand, Jonathan; Meschia, James F; Stefansson, Kari; Dichgans, Martin; Markus, Hugh S (Elsevier BV, 2012-11-01)
      Background Various genome-wide association studies (GWAS) have been done in ischaemic stroke, identifying a few loci associated with the disease, but sample sizes have been 3500 cases or less. We established the METASTROKE ...

    • Genome-wide comparative analysis of atopic dermatitis and psoriasis gives insight into opposing genetic mechanisms 

      Baurecht, Hansjörg; Hotze, Melanie; Brand, Stephan; Büning, Carsten; Cormican, Paul; Corvin, Aiden; Ellinghaus, David; Ellinghaus, Eva; Esparza-Gordillo, Jorge; Fölster-Holst, Regina; Franke, Andre; Gieger, Christian; Hubner, Norbert; Illig, Thomas; Irvine, Alan D.; Kabesch, Michael; Lee, Young A.E.; Lieb, Wolfgang; Marenholz, Ingo; McLean, W.H. Irwin; Morris, Derek W.; Mrowietz, Ulrich; Nair, Rajan; Nöthen, Markus M.; Novak, Natalija; O’Regan, Grainne M.; Schreiber, Stefan; Smith, Catherine; Strauch, Konstantin; Stuart, Philip E.; Trembath, Richard; Tsoi, Lam C.; Weichenthal, Michael; Barker, Jonathan; Elder, James T.; Weidinger, Stephan; Cordell, Heather J.; Brown, Sara J. (Elsevier BV, 2015-01-01)
      Atopic dermatitis and psoriasis are the two most common immune-mediated inflammatory disorders affecting the skin. Genome-wide studies demonstrate a high degree of genetic overlap, but these diseases have mutually exclusive ...

    • Historical gene flow constraints in a northeastern atlantic fish: phylogeography of the ballan wrasselabrus bergyltaacross its distribution range 

      Almada, Frederico; Francisco, Sara M.; Lima, Cristina S.; FitzGerald, Richard; Mirimin, Luca; Villegas-Ríos, David; Saborido-Rey, Fran; Afonso, Pedro; Morato, Telmo; Bexiga, Sérgio; Robalo, Joana I. (The Royal Society, 2017-02-01)
      The distribution and demographic patterns of marine organisms in the north Atlantic were largely shaped by climatic changes during the Pleistocene, when recurrent glacial maxima forced them to move south or to survive in ...

    • Impact of diabetes, insulin, and metformin use on the outcome of patients with human epidermal growth factor receptor 2–positive primary breast cancer: analysis from the altto phase iii randomized trial 

      Sonnenblick, Amir; Agbor-Tarh, Dominique; Bradbury, Ian; Di Cosimo, Serena; Azim, Hatem A.; Fumagalli, Debora; Sarp, Severine; Wolff, Antonio C.; Andersson, Michael; Kroep, Judith; Cufer, Tanja; Simon, Sergio D.; Salman, Pamela; Toi, Masakazu; Harris, Lyndsay; Gralow, Julie; Keane, Maccon; Moreno-Aspitia, Alvaro; Piccart-Gebhart, Martine; de Azambuja, Evandro (American Society of Clinical Oncology (ASCO), 2017-05-01)

    • in vitro selection of miltefosine resistance in promastigotes of leishmania donovani from nepal: genomic and metabolomic characterization 

      Shaw, C. D.; Lonchamp, J.; Downing, T.; Imamura, H.; Freeman, T. M.; Cotton, J. A.; Sanders, M.; Blackburn, G.; Dujardin, J. C.; Rijal, S.; Khanal, B.; Illingworth, C. J. R.; Coombs, G. H.; Carter, K. C. (Wiley-Blackwell, 2016-02-09)
      In this study, we followed the genomic, lipidomic and metabolomic changes associated with the selection of miltefosine (MIL) resistance in two clinically derived Leishmania donovani strains with different inherent resistance ...

    • Increased risk of cognitive and functional decline in patients with atrial fibrillation: results of the ontarget and transcend studies 

      Marzona, I.; O'Donnell, M.; Teo, K.; Gao, P.; Anderson, C.; Bosch, J.; Yusuf, S. (Joule Inc., 2012-02-27)
      Background: The role of atrial fibrillation in cognitive impairment and dementia, independent of stroke, is uncertain. We sought to determine the association of atrial fibrillation with cognitive and physical impairment ...

    • Inverse optical design of the human eye using likelihood methods and wavefront sensing 

      Sakamoto, Julia A.; Barrett, Harrison H.; Goncharov, Alexander V. (The Optical Society, 2008-01-01)

    • Investigation of the isoplanatic patch and wavefront aberration along the pupillary axis compared to the line of sight in the eye 

      Nowakowski, Maciej; Sheehan, Matthew; Neal, Daniel; Goncharov, Alexander V. (The Optical Society, 2012-01-03)

    • Isotopic niches of fin whales from the mediterranean sea and the celtic sea (north atlantic) 

      Das, Krishna; Holleville, Ophélie; Ryan, Conor; Berrow, Simon; Gilles, Anita; Ody, Denis; Michel, Loïc N. (Elsevier BV, 2017-06-01)

    • Legislation for smoke-free workplaces and health of bar workers in ireland: before and after study 

      Allwright, S. (BMJ, 2005-11-12)
      Objectives To compare exposure to secondhand smoke and respiratory health in bar staff in the Republic of Ireland and Northern Ireland before and after the introduction of legislation for smoke-free workplaces in the ...

    • Loss of otolith function with age is associated with increased postural sway measures 

      Serrador, Jorge M.; Lipsitz, Lewis A.; Gopalakrishnan, Gosala S.; Black, F. Owen; Wood, Scott J. (Elsevier BV, 2009-11-01)

    • Meeting the needs of visually impaired people living in lifetime homes 

      Rooney, Clíona; Hadjri, Karim; Rooney, Máirin; Faith, Verity; McAllister, Keith; Craig, Cathy (Informa UK Limited, 2016-04-02)
      This article explores perceptions on the suitability and effectiveness of Lifetime Homes standards (LTHS) for those with visual impairment in Northern Ireland. LTHS are a series of mandatory United Kingdom public-sector ...

    • Mild chronic kidney disease and functional impairment in community-dwelling older adults 

      Smyth, A.; Glynn, L. G.; Murphy, A. W.; Mulqueen, J.; Canavan, M.; Reddan, D. N.; O'Donnell, M. (Oxford University Press (OUP), 2013-02-24)
      Background: chronic kidney disease (CKD) has been associated with an increased risk of death and cardiovascular events, but its relationship with non-vascular outcomes, including functional impairment (FI), is less well ...

    • Minimum landing size for northeast atlantic stocks of deep-water red crab, chaceon affinis (milne edwards and bouvier, 1894) 

      Robinson, M. (Oxford University Press (OUP), 2008-01-17)
      Annual landings of the deep-water red crab (Chaceon affinis) in the NE Atlantic have fluctuated around 1000 t for much of the past decade, but they dropped significantly in 2006. No EU or National Member State legislation ...

    • Musculoskeletal disorders among irish farmers 

      Osborne, A.; Blake, C.; McNamara, J.; Meredith, D.; Phelan, J.; Cunningham, C. (Oxford University Press (OUP), 2010-09-15)
      Background Farming is an occupation that predisposes individuals to health problems including musculoskeletal disorders (MSDs). There is limited research regarding MSDs among farmers especially in Ireland. Aims To establish ...

    • Newly identified genetic risk variants for celiac disease related to the immune response 

      Hunt, Karen A; Zhernakova, Alexandra; Turner, Graham; Heap, Graham A R; Franke, Lude; Bruinenberg, Marcel; Romanos, Jihane; Dinesen, Lotte C; Ryan, Anthony W; Panesar, Davinder; Gwilliam, Rhian; Takeuchi, Fumihiko; McLaren, William M; Holmes, Geoffrey K T; Howdle, Peter D; Walters, Julian R F; Sanders, David S; Playford, Raymond J; Trynka, Gosia; Mulder, Chris J J; Mearin, M Luisa; Verbeek, Wieke H M; Trimble, Valerie; Stevens, Fiona M; O'Morain, Colm; Kennedy, Nicholas P; Kelleher, Dermot; Pennington, Daniel J; Strachan, David P; McArdle, Wendy L; Mein, Charles A; Wapenaar, Martin C; Deloukas, Panos; McGinnis, Ralph; McManus, Ross; Wijmenga, Cisca; van Heel, David A (Springer Nature, 2008-03-02)
      Our genome-wide association study of celiac disease previously identified risk variants in the IL2-IL21 region. To identify additional risk variants, we genotyped 1,020 of the most strongly associated non-HLA markers in ...

    • Observation and quantification of in situ animal-sediment relations using time-lapse sediment profile imagery (t-spi) 

      Solan, M; Kennedy, R (Inter-Research Science Center, 2002-01-01)
      One of the controlling factors in determining colonisation and survivorship of benthic species is the physical nature of the sediment which, in turn, is regulated by the activities of the resident infauna. This study uses ...

    • Observations of the unidentified gamma-ray source tev j2032+4130 by veritas 

      Aliu, E.; Aune, T.; Behera, B.; Beilicke, M.; Benbow, W.; Berger, K.; Bird, R.; Buckley, J. H.; Bugaev, V.; Cardenzana, J. V.; Cerruti, M.; Chen, X.; Ciupik, L.; Connolly, M. P.; Cui, W.; Duke, C.; Dumm, J.; Errando, M.; Falcone, A.; Federici, S.; Feng, Q.; Finley, J. P.; Fortin, P.; Fortson, L.; Furniss, A.; Galante, N.; Gillanders, G. H.; Griffin, S.; Griffiths, S. T.; Grube, J.; Gyuk, G.; Hanna, D.; Holder, J.; Hughes, G.; Humensky, T. B.; Kaaret, P.; Kargaltsev, Oleg; Kertzman, M.; Khassen, Y.; Kieda, D.; Krawczynski, H.; Lang, M. J.; Madhavan, A. S.; Maier, G.; Majumdar, P.; McCann, A.; Moriarty, P.; Mukherjee, R.; Nieto, D.; O'Faoláin de Bhróithe, A.; Ong, R. A.; Otte, A. N.; Pandel, D.; Perkins, J. S.; Pohl, M.; Popkow, A.; Prokoph, H.; Quinn, J.; Ragan, K.; Rajotte, J.; Reyes, L. C.; Reynolds, P. T.; Richards, G. T.; Roache, E.; Sembroski, G. H.; Skole, C.; Staszak, D.; Telezhinsky, I.; Theiling, M.; Tucci, J. V.; Tyler, J.; Varlotta, A.; Vincent, S.; Wakely, S. P.; Weekes, T. C.; Weinstein, A.; Welsing, R.; Williams, D. A.; Zitzer, B. (IOP Publishing, 2014-02-07)
      TeV J2032+4130 was the first unidentified source discovered at very high energies (VHEs; E > 100 GeV), with no obvious counterpart in any other wavelength. It is also the first extended source to be observed in VHE ...

    • Occurrence and co-occurrence of hallucinations by modality in schizophrenia-spectrum disorders 

      McCarthy-Jones, Simon; Smailes, David; Corvin, Aiden; Gill, Michael; Morris, Derek W.; Dinan, Timothy G.; Murphy, Kieran C.; Anthony O′Neill, F.; Waddington, John L.; Australian Schizophrenia Research Bank,; Donohoe, Gary; Dudley, Robert (Elsevier BV, 2017-06-01)
      It is not only unclear why hallucinations in schizophrenia occur with different prevalence by modality, but also to what extent they do. Reliable prevalence estimates of hallucinations by modality in schizophrenia are ...

    • Poor health and loneliness in later life: the role of depressive symptoms, social resources, and rural environments 

      Burholt, V.; Scharf, T. (Oxford University Press (OUP), 2013-12-10)
      Objectives. We draw on cognitive discrepancy theory to hypothesize and test a pathway from poor health to loneliness in later life. We hypothesize that poor health will have a negative influence on social participation and ...