Browsing University of Galway Support Services by Subject "autoimmunity"
Now showing items 1-8 of 8
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Concise review: adult mesenchymal stromal cell therapy for inflammatory diseases: how well are we joining the dots?
(Wiley-Blackwell, 2013-10-01)Mesenchymal stromal (stem) cells (MSCs) continue to be a strong area of focus for academic- and industry-based researchers who share the goal of expanding their therapeutic use for diverse inflammatory and immune-mediated ... -
Distinctive surface glycosylation patterns associated with mouse and human cd4+ regulatory t cells and their suppressive function
(Frontiers Media SA, 2017-08-21)Regulatory T-cells (Treg) are essential for maintaining immune homeostasis and tolerance. Surface glycosylation is ubiquitous on mammalian cells and regulates diverse biological processes. While it is currently well accepted ... -
Immunological research in clinical psychiatry: report on the consensus debate during the 7th expert meeting on psychiatry and immunology
(Springer Nature, 2002-01-01)There is convincing evidence that cytokines are involved in the physiology and pathophysiology of brain function and interact with different neurotransmitter and neuroendocrine pathways. The possible involvement of the ... -
Invariant natural killer t cells and their ligands: focus on multiple sclerosis
(Wiley-Blackwell, 2015-06-25)Invariant natural killer T (iNKT) cells are an innate population of T cells identified by the expression of an invariant T-cell receptor and reactivity to lipid-based antigens complexed with CD1d. They account for a small ... -
Neurofilament light as an immune target for pathogenic antibodies
(Wiley-Blackwell, 2017-08-11)Antibodies to neuronal antigens are associated with many neurological diseases including paraneoplastic neurological disorders, epilepsy, amyotrophic lateral sclerosis and multiple sclerosis. Immunization with neuronal ... -
Regulating immunogenicity and tolerogenicity of bone marrow-derived dendritic cells through modulation of cell surface glycosylation by dexamethasone treatment
(Frontiers Media SA, 2017-10-30)Dendritic cellular therapies and dendritic cell vaccines show promise for the treatment of autoimmune diseases, the prolongation of graft survival in transplantation, and in educating the immune system to fight cancers. ... -
Relationship of blood group determinants on helicobacter pylori lipopolysaccharide with host lewis phenotype and inflammatory response
(American Society for Microbiology, 2000-02-01)As Lewis a (Le(a)) and Lewis b (Le(b)) blood group antigens are isoforms of Lewis x (Le(x)) and Lewis y (Le(y)) and are expressed in the gastric mucosa, we evaluated whether the patterns of expression of Le(x) and Le(y) ... -
Structural studies on lipopolysaccharides of serologically non-typable strains of helicobacter pylori, af1 and 007, expressing lewis antigenic determinants
(Wiley-Blackwell, 1999-11-15)In contrast to other Helicobacter pylori strains, which have serologically detectable Lewis(x) (Le(x)) and Lewis(y) (Le(y)) antigenic determinants in the O-specific polysaccharide chains of the lipopolysaccharides, H. ...