Browsing University of Galway Support Services by Author "Gabba, Adele"
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Synthesis and biological evaluation of migrastatin macrotriazoles
Gabba, Adele; Robakiewicz, Stefania; Taciak, Bartłomiej; Ulewicz, Katarzyna; Broggini, Gianluigi; Rastelli, Giulio; Krol, Magadalena; Murphy, Paul V.; Passarella, Daniele (Wiley-Blackwell, 2016-12-05)The synthesis of three macrotriazoles that are analogues of migrastatin is reported. The synthesis is based on copper(I)- and ruthenium-catalyzed azide-alkyne cycloaddition reactions. The enantiopure terminal alkyne ...