Browsing University of Galway Support Services by Author "Kaiser, Marcel"
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2-octadecynoic acid as a dual life stage inhibitor of plasmodium infections and plasmodial fas-ii enzymes
Carballeira, Néstor M.; Bwalya, Angela Gono; Itoe, Maurice Ayamba; Andricopulo, Adriano D.; Cordero-Maldonado, María Lorena; Kaiser, Marcel; Mota, Maria M.; Crawford, Alexander D.; Guido, Rafael V.C.; Tasdemir, Deniz (Elsevier BV, 2014-09-01) -
Assessment of dual life stage antiplasmodial activity of british seaweeds
Spavieri, Jasmine; Allmendinger, Andrea; Kaiser, Marcel; Itoe, Maurice; Blunden, Gerald; Mota, Maria; Tasdemir, Deniz (MDPI AG, 2013-10-22)Terrestrial plants have proven to be a prolific producer of clinically effective antimalarial drugs, but the antimalarial potential of seaweeds has been little explored. The main aim of this study was to assess the in vitro ... -
Bifurcatriol, a new antiprotozoal acyclic diterpene from the brown alga bifurcaria bifurcata
Smyrniotopoulos, Vangelis; Merten, Christian; Kaiser, Marcel; Tasdemir, Deniz (MDPI AG, 2017-08-02)Linear diterpenes that are commonly found in brown algae are of high chemotaxonomic and ecological importance. This study reports bifurcatriol (1), a new linear diterpene featuring two stereogenic centers isolated from the ... -
Lycopodium clavatum and lycopodium complanatum subsp. chamaecyparissus ekstrelerinin antiprotozoal aktivitesi ve sitotoksisitesi
Erdogan Orhan, Ilkay; Sener, Bilge; Kaiser, Marcel; Brun, Reto; Tasdemir, Deniz; Erdogan Orhan, Ilkay (LookUs Bilisim, Ltd., 2013-01-01)Objective: We assessed in vitro antiprotozoal activity of the petroleum ether (PE), chloroform (CHCl3), methanol (MeOH) and alkaloid (ALK) extracts of the ferns Lycopodium clavatum L. (LC) and L. complanatum L. subsp. ... -
Natural and semisynthetic analogues of manadoperoxide b reveal new structural requirements for trypanocidal activity
Chianese, Giuseppina; Scala, Fernando; Calcinai, Barbara; Cerrano, Carlo; Dien, Henny; Kaiser, Marcel; Tasdemir, Deniz; Taglialatela-Scafati, Orazio (MDPI AG, 2013-08-28)Chemical analysis of the Indonesian sponge Plakortis cfr. lita afforded two new analogues of the potent trypanocidal agent manadoperoxide B (1), namely 12-isomanadoperoxide B (2) and manadoperoxidic acid B (3). These ...