Now showing items 1-6 of 6

  • Expression of RHOGTPase regulators in human myometrium 

    Mullins, Brian; O'Brien, Margaret; Flynn, David; Smith, Terry; Morrison, John J. (Reproductive Biology and Endocrinology, 2008-01-11)
    Background: RHOGTPases play a significant role in modulating myometrial contractility in uterine smooth muscle. They are regulated by at least three families of proteins, RHO guanine nucleotide exchange factors (RHOGEFs), ...
  • Ghrelin in the human myometrium 

    O'Brien, Margaret; Earley, Padraig; Morrison, John J.; Smith, Terry (BioMed Central Ltd, 2010-03-29)
    Ghrelin is a 28-amino acid octanolyated peptide, synthesised primarily in the stomach. It stimulates growth hormone release, food intake and exhibits many other diverse effects. Our group have previously determined that ...
  • Ghrelin in the human myometrium 

    Smith, Terry; O'Brien, Margaret; Morrison, John J. (2010)
    Background: Ghrelin is a 28-amino acid octanolyated peptide, synthesised primarily in the stomach. It stimulates growth hormone release, food intake and exhibits many other diverse effects. Our group have previously ...
  • Modulation of human uterine smooth muscle cell collagen contractility by thrombin, Y-27632, TNF alpha and indomethacin 

    Morrison, John J.; Smith, Terry; O'Brien, Margaret; Fitzgibbon, Joan (Springer, 2009-01-08)
    Background: Preterm labour occurs in approximately 10% of pregnancies and is a major cause of infant morbidity and mortality. However, the pathways involved in regulating contractility in normal and preterm labour are ...
  • Modulation of human uterine smooth muscle cell collagen contractility by thrombin, Y-27632, TNF alpha and indomethacin 

    Fitzgibbon, Joan; Morrison, John J.; Smith, Terry; O'Brien, Margaret (BioMed Central, 2009-01-08)
    Background: Preterm labour occurs in approximately 10% of pregnancies and is a major cause of infant morbidity and mortality. However, the pathways involved in regulating contractility in normal and preterm labour are not ...
  • Oxytocic plant cyclotides as templates for peptide G protein-coupled receptor ligand design 

    O'Brien, Margaret; Smith, Terry (National Academy Of Sciences Of The United States Of America, 2013-10-23)
    Cyclotides are plant peptides comprising a circular backbone and three conserved disulfide bonds that confer them with exceptional stability. They were originally discovered in Oldenlandia affinis based on their use in ...