Browsing Pharmacology & Therapeutics (Scholarly Articles) by Author "SFI"
Now showing items 1-4 of 4
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The endocannabinoid system in the rat dorsolateral periaqueductal grey mediates fear-conditioned analgesia and controls fear expression in the presence of nocicpetive tone
Olango, W.M.; Roche, Michelle; Ford, Gemma K.; Harhen, Brendan; Finn, David P. (Wiley, 2011)Background and purpose: Endocannabinoids in the midbrain periaqueductal grey (PAG) are involved in modulating nociception and unconditioned stress-induced analgesia, however, their role in fear-conditioned analgesia (FCA) ... -
Modulation of Conditioned Fear, Fear-Conditioned Analgesia, and Brain Regional C-Fos Expression Following Administration of Muscimol into the Rat Basolateral Amygdala
Rea, Kieran; Roche, Michelle; Finn, David P. (Elsevier, 2011-04)Evidence suggests that gamma-aminobutyric acid (GABA) signalling in the basolateral amygdala (BLA) is involved in pain, fear, and fear-conditioned analgesia (FCA). In this study, we investigated the effects of intra-BLA ... -
Molecular and electrophysiological changes in the prefrontal cortex-amygdala-dorsal periaqueductal grey pathway during persistent pain state and fear-conditioned analgesia
Butler, Ryan K.; Finn, David P. (Elsevier, 2011-10)Fear-conditioned analgesia (FCA) is the reduction in pain responding which is expressed upon re-exposure to a context previously paired with an aversive stimulus. Projections along the prefrontal cortex (PFC)¿amygdala¿dorsal ... -
A role for the ventral hippocampal endocannabinoid system in fear-conditioned analgesia and fear responding in the presence of nociceptive tone in rats.
Ford, Gemma K.; Kieran, Siobhan; Dolan, Kenneth; Harhen, Brendan; Finn, David P. (Elsevier, 2011-08)The endogenous cannabinoid (endocannabinoid) system plays an important role in fear-conditioned analgesia (FCA) and expression and extinction of conditioned fear. The hippocampus has an established role in both pain and ...