Browsing School of Medicine by Author "Heneghan, Helen M."
Now showing items 1-3 of 3
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The KRAS-Variant Is Associated with Risk of Developing Double Primary Breast and Ovarian Cancer
Kerin, Michael J.; McVeigh, Terri; Dorairaj, Jemima J.; Heneghan, Helen M.; Miller, Nicola (2012)Purpose: A germline microRNA binding site-disrupting variant, the KRAS-variant (rs61764370), is associated with an increased risk of developing several cancers. Because this variant is most strongly associated with ovarian ... -
Modern management of pyogenic hepatic abscess: a case series and review of the literature
Heneghan, Helen M.; Healy, Nuala A. (BioMed Central, 2011-03)Background Pyogenic hepatic abscesses are relatively rare, though untreated are uniformly fatal. A recent paradigm shift in the management of liver abscesses, facilitated by advances in diagnostic and interventional ... -
Relationship between circulating and tissue microRNAs in a murine model of breast cancer.
Waters, Peadar S.; McDermott, Ailbhe M.; Wall, Deirdre; Heneghan, Helen M.; Miller, Nicola; Newell, John; Kerin, Michael J.; Dwyer, Róisín M. (2012)MiRNAs are key regulators of tumorigenesis that are aberrantly expressed in the circulation and tissue of patients with cancer. The aim of this study was to determine whether miRNA dysregulation in the circulation reflected ...