Browsing School of Medicine by Subject "HPA axis"
Now showing items 1-5 of 5
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Behavioural, neurochemical and neuroendocrine effects of the endogenous beta-carboline harmane in fear-conditioned rats
(2012)The putative endogenous imidazoline binding site ligand harmane enhances neuronal activation in response to psychological stress and alters behaviour in animal models of anxiety and antidepressant efficacy. However, the ... -
Pharmacological inhibition of endocannabinoid degradation modulates the expression of inflammatory mediators in the hypothalamus following an immunological stressor
(Elsevier, 2011-09)The endocannabinoid system is an important regulator of the nervous, neuroendocrine, and immune systems, thus representing a novel therapeutic target for stress-related neuroinflammatory and psychiatric disorders. However, ... -
Pharmacological inhibition of endocannabinoid degradation modulates the expression of inflammatory mediators in the rat hypothalamus following an immunological stressor
(2012)The endocannabinoid system is an important regulator of the nervous, neuroendocrine and immune systems, thus representing a novel therapeutic target for stress-related neuroinflammatory and psychiatric disorders. However, ... -
Psychological stress in early life as a predisposing factor for the development of chronic pain: Clinical and preclinical evidence and neurobiological mechanisms
(Wiley, 2016-07-12)A wealth of research over the past 2 decades has expanded our understanding of the impact of early-life adversity on physiological function and, consequently, health and wellbeing in later life. Early-life adversity increases ...