Browsing College of Medicine, Nursing and Health Sciences by Subject "Breast cancer"

Now showing items 1-6 of 6

    • Influence of stromal–epithelial interactions on breast cancer in vitro and in vivo 

      Potter, Shirley M.; Dwyer, Róisín M.; Hartmann, Marion C.; Khan, Sonja; Boyle, Marie P.; Curran, Catherine E.; Kerin, Michael J. (Springer, 2011-02-23)
      Stromal cell-secreted chemokines including CCL2 have been implicated in the primary tumor microenvironment, as mediators of tumor cell migration, proliferation, and angiogenesis. Expression of CCL2 and its principal receptor ...

    • Influences on quality of prescribing in breast cancer patients 

      O'Reilly, Helen Anne; Dowling, Maura (Mark Allen Healthcare, 2016-10-13)
      This article presents a discussion on both positive and negative influences on quality of prescribing in clinical practice. It explores how such influences have an impact on breast cancer patients on adjuvant hormonal ...

    • Isolation of secreted microRNAs (miRNAs) from cell-conditioned media 

      Glynn, Claire L.; Khan, Sonja; Kerin, Michael J.; M. Dwyer, Roisin (2013)
      MicroRNAs (miRNAs) have been found to be stable in the circulation of cancer patients raising their potential as circulating biomarkers of disease. The specific source and role, however, of miRNAs in the circulation is ...

    • Relationship between CCL5 and transforming growth factor-β1 (TGFβ1) in breast cancer 

      Hartmann, Marion C.; Dwyer, Róisín M.; Costello, M.; Potter, Shirley M.; Curran, Catherine E.; Hennessy, Emer; Newell, John; Griffin, Damian G.; Kerin, Michael J. (Elsevier, 2011-06-12)
      Purpose Investigate circulating CCL5 in breast cancer patients and healthy controls, along with gene expression levels in corresponding tumour tissue and isolated primary stromal cells. Hormonal control of CCL5, and a ...

    • Systemic chemokine levels in breast cancer patients and their relationship with circulating menstrual hormones 

      Potter, Shirley M.; Dwyer, Róisín M.; Curran, Catherine E.; Hennessy, Emer; Harrington, Kate A.; Griffin, Damian G.; Kerin, Michael J. (Springer, 2008-06-04)
      Introduction The chemokines Stromal Cell-Derived Factor-1 alpha (SDF-1 alpha/CXCL12) and Monocyte Chemotactic Protein-1 (MCP-1/CCL2) have been implicated in breast cancer progression. We recently reported elevated systemic ...

    • Vitamin D supplementation and clinical outcomes in cancer survivorship 

      Griffin, Niamh; Dowling, Maura (Mark Allen Healthcare, 2018-10-22)
      Increasing evidence points to the role of vitamin D supplementation in cancer management. A comprehensive search of online databases was undertaken for all research studies relating to vitamin D supplementation in cancer ...