Browsing College of Medicine, Nursing and Health Sciences by Author "Newell, John"
Now showing items 1-14 of 14
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A cluster randomised controlled trial evaluating the effectiveness of a structured pulmonary rehabilitation education programme for improving the health status of people with chronic obstructive pulmonary disease (COPD): The PRINCE Study protocol.
Murphy, Kathy; Casey, Dympna; Devane, Declan; Cooney, Adeline; McCarthy, Bernard; Mee, Lorraine; Ní Chúlain, Martina; Murphy, Andrew W.; Newell, John; O'Shea, Eamon (BioMed Central, 2011-01-18)A key strategy in improving care for people with chronic obstructive pulmonary disease (COPD) is the provision of pulmonary rehabilitation programmes. Pulmonary rehabilitation programmes have been successful in improving ... -
Comparing the clinical-effectiveness and cost-effectiveness of an internet-delivered Acceptance and Commitment Therapy (ACT) intervention with a waiting list control among adults with chronic pain: study protocol for a randomised controlled trial
Hayes, Sara; Hogan, Michael; Dowd, Haulie; Doherty, Edel; O'Higgins, Siobhan; Nic Gabhainn, Saoirse; MacNeela, Padraig; Murphy, Andrew W.; Kropmans, Thomas; O'Neill, Ciaran; Newell, John; McGuire, Brian E. (BMJ Publishing Group, 2014-07-02)Internet-delivered psychological interventions among people with chronic pain have the potential to overcome environmental and economic barriers to the provision of evidence-based psychological treatment in the Irish health ... -
Effect of tailored practice and patient care plans on secondary prevention of heart disease in general practice: cluster randomised controlled trial.
Murphy, Andrew W.; Byrne, Molly; Newell, John (2009)Objective To test the effectiveness of a complex intervention designed, within a theoretical framework, to improve outcomes for patients with coronary heart disease. Design Cluster randomised controlled multicentre trial. ... -
An evaluation of MyAction, a community-based lifestyle and medical risk factor modification programme, in women with prior gestational diabetes mellitus: study protocol for a randomised controlled trial
Infanti, Jennifer J.; Dunne, Fidelma P.; Gillespie, Paddy; Glynn, Liam G.; Noctor, Eoin; Newell, John; McGuire, Brian E.; O'Dea, Angela (BioMed Central, 2013-05-02)Universal screening using the International Association of Diabetes and Pregnancy Study Groups (IADPSG) criteria has identified a prevalence of gestational diabetes mellitus (GDM) of 12.4% in women living in Ireland. Women ... -
Feasibility of a physical activity programme embedded into the daily lives of older adults living in nursing homes: protocol for a randomised controlled pilot feasibility study
Barrett, Eva; Gillespie, Paddy; Newell, John; Casey, Dympna (BMC, 2018-04-20)Background: Older adults living in nursing homes spend the majority of their time inactive. The associated levels of chronic disease places an increasing burden on healthcare systems. Physical activity (PA) interventions ... -
The Irish DAFNE Study Protocol: A cluster randomised trial of group versus individual follow-up after structured education for Type 1 diabetes
Dinneen, Seán F.; O' Hara, Mary Clare; Byrne, Molly; Newell, John; Daly, Lisa (2009)Background: Structured education programmes for individuals with Type 1 diabetes have become a recognised means of delivering the knowledge and skills necessary for optimal self-management of the condition. The Dose ... -
miR-379 Regulates Cyclin B1 Expression and Is Decreased in Breast Cancer
Khan, Sonja; Brougham, Cathy L.; Ryan, James; Sahrudin, Arisha; O'Neill, Gregory; Wall, Deirdre; Curran, Catherine; Newell, John; Kerin, Michael J.; Dwyer, Róisín M. (2013)MicroRNAs are small non-coding RNA molecules that control gene expression post-transcriptionally, and are known to be altered in many diseases including breast cancer. The aim of this study was to determine the relevance ... -
Predictors of quality of life gains among people with type 1 diabetes participating in the Dose Adjustment for Normal Eating (DAFNE) structured education programme
Byrne, Molly; Newell, John; Coffey, Norma; O' Hara, Mary Clare; Dinneen, Sean (Elsevier, 2012-11)Aims: To examine predictors of quality of life gains among people with type 1 diabetes following the Dose Adjustment for Normal Eating (DAFNE) self-management training programme.Methods: Clinical and questionnaire data ... -
Reasons for participation and non-participation in a diabetes prevention trial among women with prior gestational diabetes mellitus (GDM)
Infanti, Jennifer J.; O'Dea, Angela; McGuire, Brian E.; Newell, John; Glynn, Liam G.; O'Neill, Ciaran; Connolly, Susan B.; Dunne, Fidelma P. (Springer, 2014-01)Background: Gestational diabetes mellitus (GDM) is a risk factor for the development of type 2 diabetes. Lifestyle intervention can prevent progression to type 2 diabetes in high risk populations. We designed a randomised ... -
Relationship between CCL5 and transforming growth factor-β1 (TGFβ1) in breast cancer
Hartmann, Marion C.; Dwyer, Róisín M.; Costello, M.; Potter, Shirley M.; Curran, Catherine E.; Hennessy, Emer; Newell, John; Griffin, Damian G.; Kerin, Michael J. (Elsevier, 2011-06-12)Purpose Investigate circulating CCL5 in breast cancer patients and healthy controls, along with gene expression levels in corresponding tumour tissue and isolated primary stromal cells. Hormonal control of CCL5, and a ... -
Relationship between circulating and tissue microRNAs in a murine model of breast cancer.
Waters, Peadar S.; McDermott, Ailbhe M.; Wall, Deirdre; Heneghan, Helen M.; Miller, Nicola; Newell, John; Kerin, Michael J.; Dwyer, Róisín M. (2012)MiRNAs are key regulators of tumorigenesis that are aberrantly expressed in the circulation and tissue of patients with cancer. The aim of this study was to determine whether miRNA dysregulation in the circulation reflected ... -
Screening uptake rates and the clinical and cost effectiveness of screening for gestational diabetes mellitus in primary versus secondary care: study protocol for a randomised controlled trial
O¿Dea, Angela; Infanti, Jennifer J; Gillespie, Paddy; Tummon, Olga; Fanous, Samuel; Glynn, Liam G; McGuire, Brian E; Newell, John; Dunne, Fidelma P (BioMed Central, 2014-01-17)Background: The risks associated with gestational diabetes mellitus (GDM) are well recognized, and there is increasing evidence to support treatment of the condition. However, clear guidance on the ideal approach to screening ... -
Screening uptake rates and the clinical and cost effectiveness of screening for gestational diabetes mellitus in primary versus secondary care: study protocol for a randomised controlled trial
O'Dea, Angela; Infanti, Jennifer J.; Gillespie, Paddy; Tummon, Olga; Fanous, Samuel; Glynn, Liam G.; McGuire, Brian; Newell, John (BioMed Central, 2014-01-17)The risks associated with gestational diabetes mellitus (GDM) are well recognized, and there is increasing evidence to support treatment of the condition. However, clear guidance on the ideal approach to screening for GDM ... -
The Sodium Iodide Symporter (NIS) and Potential Regulators in Normal, Benign and Malignant Human Breast Tissue
Ryan, James; Curran, Catherine E.; Hennessy, Emer; Newell, John; Kerin, Michael J.; Dwyer, Róisín M. (2011-01)Introduction: The presence, relevance and regulation of the Sodium Iodide Symporter (NIS) in human mammary tissue remains poorly understood. This study aimed to quantify relative expression of NIS and putative regulators ...