Browsing College of Medicine, Nursing and Health Sciences by Title
Now showing items 352-371 of 853
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High CerS5 expression levels associate with reduced patient survival and transition from apoptotic to autophagy signalling pathways in colorectal cancer
(Wiley, 2014-11-13)Ceramide synthase 5 is involved in the de novo synthesis of ceramide, a sphingolipid involved in cell death and proliferation. In this study, we investigated the role of ceramide synthase 5 in colorectal cancer by examining ... -
High risk HPV testing following treatment for cervical intraepithelial neoplasia
(Springer Verlag, 2015-12-21)To determine the results of combined cytology and high-risk human papilloma virus (HR HPV) tests at 6 and 18 months postcolposcopy treatment at one Irish colposcopy centre.All women who attended the centre's colposcopy ... -
High times for painful blues: the endocannabinoid system in pain-depression comorbidity
(Oxford University Press (OUP), 2015-09-05)Depression and pain are two of the most debilitating disorders worldwide and have an estimated cooccurrence of up to 80%. Comorbidity of these disorders is more difficult to treat, associated with significant disability ... -
Histological characterization of white clots retrieved by mechanical thrombectomy from acute ischemic stroke patients
(SAGE Publications, 2019-01-01)Introduction: Advances in mechanical thrombectomy have created the unique opportunity to study the acute ischemic stroke clot material. However, there is a lack of uniformity in the histopathologic characterization of ... -
Histological stroke clot analysis after thrombectomy: Technical aspects and recommendations
(SAGE Publications, 2019-11-03)The recent advent of endovascular procedures has created the unique opportunity to collect and analyze thrombi removed from cerebral arteries, instigating a novel subfield in stroke research. Insights into thrombus ... -
HIV-related stigma in healthcare settings in Ireland: Findings from a collaborative joint stakeholder study
(Health Promotion Research Centre, University of Galway and HIV Ireland, 2023)[No abstract available] -
Home administration of bortezomib: Making a difference to myeloma patients' lives
(Elsevier, 2009-10-08)Multiple myeloma is a clonal malignancy of plasma cells, characterized by anaemia, renal dysfunction, lytic bone lesions and the presence of excess monoclonal immunoglobulin. It is the second most common hematological ... -
Home detection of freezing of gait using support vector machines through a single waist-worn triaxial accelerometer
(Public Library of Science, 2017-02-15)Among Parkinson's disease (PD) symptoms, freezing of gait (FoG) is one of the most debilitating. To assess FoG, current clinical practice mostly employs repeated evaluations over weeks and months based on questionnaires, ... -
How do nurses use the early warning score in their practice? A case study from an acute medical unit
(Wiley, 2018-10-14)Aims and objectives This study aimed to describe how nurses use the early warning score (EWS) in an acute medical ward and their compliance with the EWS and explore their views and experiences of the EWS. Background early ... -
How does ReDO®-10 work? Understanding the mechanisms of action of an intervention focused on daily activities and health from the perspective of participants
(Elsevier, 2022-05-04)Evaluation of a complex healthcare intervention should include careful exploration of the mechanisms through which it brings about change. This paper describes a qualitative evaluation of the Redesigning Daily Occupations ... -
How exactly do politics play a part in determining health? New perspectives on an age old issue.
(BMJ Group, 2002-06)This is the latest study to demonstrate an association between type of political pattern and health status, in this case suicide. Previous studies have also identified a more general relation between party political voting ... -
How far the zone of heat-induced transient block extends beyond the lesion during RF catheter cardiac ablation
(Taylor and Francis Group, 2023-01-02)Purpose While radiofrequency catheter ablation (RFCA) creates a lesion consisting of the tissue points subjected to lethal heating, the sublethal heating (SH) undergone by the surrounding tissue can cause transient ... -
How intramyocardial fat can alter the electric field distribution during Pulsed Field Ablation (PFA): Qualitative findings from computer modeling
(Public Library of Science, 2023-11-02)Even though the preliminary experimental data suggests that cardiac Pulsed Field Ablation (PFA) could be superior to radiofrequency ablation (RFA) in terms of being able to ablate the viable myocardium separated from the ... -
How robust is the evidence for recommending very low salt intake in entire populations?
(Elsevier, 2016-10-03)[No abstract available] -
How subject animacy constrains motion event descriptions: Evidence from sequential and simultaneous bilinguals in French and English
(John Benjamins Publishing, 2017-08-09)Research has indicated that during sentence processing, French native speakers predominantly rely upon lexico-semantic cues (i.e., animacy) while native speakers of English rely upon syntactic cues (i.e., word order). The ... -
How well protected are sexually active 15 year olds? Cross national patterns in condom and contraceptive pill use 2002 - 2006.
(Springer, 2009)Objectives - To present comparative data on sexual initiation, and condom use and contraceptive pill use at last intercourse among adolescents in Europe, Israel and Canada. Methods - Data were collected by self-report ... -
Hurling Alone? How social capital failed to save the Irish from cardiovascular disease in the United States
(American Public Health Association, 2004-03-18)Objectives: We performed a historical review of cardiovascular risk profiles of Irish immigrants to the United States, 1850-1970, in regard to lifestyle, socioeconomic circumstances, and social capital. Methods: We ... -
Hydroxycinnamic acid amide derivatives of polyamines reverse spermine-induced CNS excitation
(Elsevier, 2015-03-28)The aim of this study was to examine the acute effect of a range of novel hydroxycinnamic acid derivatives of spermine on the development of spermine-induced CNS excitation and convulsions in female Laca mice, and to assess ... -
Hyporesponsivity to mu-opioid receptor agonism in the Wistar-Kyoto rat model of altered nociceptive responding associated with negative affective state.
(Lippincott, Williams & Wilkins, 2020-08-17)Chronic pain is often comorbid with anxiety and depression, altering the level of perceived pain, which negatively affects therapeutic outcomes. The role of the endogenous mu-opioid receptor (MOP) system in pain-negative ... -
Hypoxia activates the PTHrP-MEF2C pathway to attenuate hypertrophy in mesenchymal stem cell derived cartilage
(Nature Research, 2019-09-16)Articular cartilage lacks an intrinsic repair capacity and due to the ability of mesenchymal stem cells (MSCs) to differentiate into chondrocytes, MSCs have been touted as a cellular source to regenerate damaged cartilage. ...