Browsing College of Medicine, Nursing and Health Sciences by Author "http://dx.doi.org/10.13039/501100001634"
Now showing items 1-5 of 5
-
Characterisation of peroxisome proliferator-activated receptor signalling in the midbrain periaqueductal grey of rats genetically prone to heightened stress, negative affect and hyperalgesia
Okine, Bright N.; Gaspar, Jessica C.; Madasu, Manish K.; Olango, Weredeselam M.; Harhen, Brendan; Roche, Michelle; Finn, David P. (Elsevier, 2016-12-01)The stress-hyperresponsive Wistar-Kyoto (WRY) rat strain exhibits a hyperalgesic phenotype and is a useful genetic model for studying stress-pain interactions. Peroxisome proliferator-activated receptor (PPAR) signalling ... -
A cognitive occupation-based programme for people with multiple sclerosis: a study to test feasibility and clinical outcomes
Reilly, Sean; Hynes, Sinéad M. (Hindawi Publishing Corporation, 2018-05-02)Cognitive impairments are common in MS and affect personal, social, and occupational functioning. There is a developing body of evidence highlighting the role of cognitive rehabilitation, but there is still no evidence for ... -
PPARs and pain
Okine, Bright N.; Gaspar, Jessica C.; Finn, David P. (Wiley, 2018-04-21)Chronic pain is a common cause of disability worldwide and remains a global health and socio-economic challenge. Current analgesics are either ineffective in a significant proportion of patients with chronic pain or ... -
A qualitative study of the development of health literacy capacities of participants attending a community-based cardiovascular health programme
McKenna, Verna P.; Sixsmith, Jane; Barry, Margaret M. (MDPI, 2018-06-02)Health literacy is a critical determinant of health, which can empower individuals and lead to engagement in collective health promotion action and is also a crucial component in the self-management of illness. The current ... -
Ulk4 regulates GABAergic signaling and anxiety-related behavior
Liu, Min; Fitzgibbon, Marie; Wang, Yanqin; Reilly, Jamie; Qian, Xiaohong; O’Brien, Timothy; Clapcote, Steve; Shen, Sanbing; Roche, Michelle (Springer Nature, 2018-02-02)Excitation/inhibition imbalance has been proposed as a fundamental mechanism in the pathogenesis of neuropsychiatric and neurodevelopmental disorders, in which copy number variations of the Unc-51 like kinase 4 (ULK4) gene ...