Browsing Data Science Institute by Author "Nounu, Aayah"
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Biological applications of knowledge graph embedding models
Mohamed, Sameh K.; Nounu, Aayah; Nováček, Vít (Oxford University Press (OUP), 2020-02-17)Complex biological systems are traditionally modelled as graphs of interconnected biological entities. These graphs, i.e. biological knowledge graphs, are then processed using graph exploratory approaches to perform different ... -
Discovering protein drug targets using knowledge graph embeddings
Mohamed, Sameh K.; Nováček, Vít; Nounu, Aayah (Oxford University Press, 2019-08-01)Motivation Computational approaches for predicting drug-target interactions (DTIs) can provide valuable insights into the drug mechanism of action. DTI predictions can help to quickly identify new promising (on-target) ... -
Drug target discovery using knowledge graph embeddings
Mohamed, Sameh K.; Nováček, Vít; Nounu, Aayah (Association for Computing Machinery, 2019-04-08)The field of drug discovery has entered a plateau stage lately. It is increasingly more expensive and time-demanding to introduce new drugs into the market. One of the main reasons is the slow progress in finding novel ...