Now showing items 1-3 of 3

    • Biological applications of knowledge graph embedding models 

      Mohamed, Sameh K.; Nounu, Aayah; Nováček, Vít (Oxford University Press (OUP), 2020-02-17)
      Complex biological systems are traditionally modelled as graphs of interconnected biological entities. These graphs, i.e. biological knowledge graphs, are then processed using graph exploratory approaches to perform different ...
    • Discovering protein drug targets using knowledge graph embeddings 

      Mohamed, Sameh K.; Nováček, Vít; Nounu, Aayah (Oxford University Press, 2019-08-01)
      Motivation Computational approaches for predicting drug-target interactions (DTIs) can provide valuable insights into the drug mechanism of action. DTI predictions can help to quickly identify new promising (on-target) ...
    • Drug target discovery using knowledge graph embeddings 

      Mohamed, Sameh K.; Nováček, Vít; Nounu, Aayah (Association for Computing Machinery, 2019-04-08)
      The field of drug discovery has entered a plateau stage lately. It is increasingly more expensive and time-demanding to introduce new drugs into the market. One of the main reasons is the slow progress in finding novel ...