Now showing items 14-16 of 16

  • Permissive roles of cytokines Interleukin-7 and Flt3-ligand in mouse B cell lineage commitment 

    von Muenchow, Lilly; Alberti-Servera, Llucia; Klein, Fabian; Capoferri, Giuseppina; Finke, Daniela; Ceredig, Rhodri; Rolink, Antonius; Tsapogas, Panagiotis (National Academy of Sciences, 2016-11-04)
    Hematopoietic cells are continuously generated throughout life from hematopoietic stem cells, thus making hematopoiesis a favorable system to study developmental cell lineage commitment. The main factors incorporating ...
  • Pro-B cells propagated in stromal cell-free cultures reconstitute functional B-cell compartments in immunodeficient mice 

    von Muenchow, Lilly; Tsapogas, Panagiotis; Albertí-Servera, Llucia; Capoferri, Giuseppina; Doelz, Marianne; Rolink, Hannie; Bosco, Nabil; Ceredig, Rhodri; Rolink, Antonius G. (Wiley, 2016-12-28)
    Up to now long-term in vitro growth of pro-B cells was thought to require stromal cells. However, here we show that fetal liver (FL) and bone marrow (BM) derived pro-B cells can be propagated long-term in stromal cell-free ...
  • Sterile post-traumatic immunosuppression 

    Islam, Md Nahidul; Bradley, Benjamin A.; Ceredig, Rhodri (Nature Publishing Group, 2016-04-29)
    After major trauma, the human immune system initiates a series of inflammatory events at the injury site that is later followed by suppression of local inflammation favoring the repair and remodeling of the damaged tissues. ...